Heine is both a surname and a given name of German origin. People with that name include:

• Albert Heine (1867–1949), German actor
• Alice Heine (1858–1925), American-born princess of Monaco
• Armand Heine (1818–1883), French banker and philanthropist
• Ben Heine (born 1983), Belgian visual artist and music producer
• Bernd Heine (born 1939), German linguist and Afrikanist
• Bernhard Heine (1800–1846), German physician and bone specialist
• Bill Heine (1945–2019), British radio presenter
• Bud Heine (1900–1976), American baseball player
• Cariba Heine (born 1988), Australian actress
• Carl Wilhelm Heine (1838–1877), German surgeon
• Charles Heiné (1920–1971), French footballer
• Dwight Heine (1919-1984), Marshallese politician
• Eduard Heine (1821–1881), German mathematician
• Edmund Carl Heine, German convicted of espionage in 1941
• Ellen Heine (1907–1989), botanist, photographer and painter
• Ferdinand Heine (1809–1894), German ornithologist and collector
• Ferdinand Heine (junior) (1840–1920), German plant breeder and ornithologist
• Friedrich Wilhelm Heine (1845–1921), German painter
• Gustav Heine von Geldern (1812–1886), Austrian publicist
• Gustav Otto Ludolf Heine (1868–1959), German-American piano business owner and automobile builder
• Harry Heine (1928–2004), Canadian maritime and landscape painter
• Heinrich Heine (1797–1856), German poet
• Helme Heine (born 1941), German children's book author
• Hilda Heine (born 1951), Marshallese educator and politician, President of the Marshall Islands
• Jared Heine (born 1984), Marshallese swimmer
• Joseph Heine (1803–1877), German physician and civil servant
• Jakob Heine (1800–1879), German orthopaedist
• Johann Georg Heine (1771–1838), German orthopaedist and doctor
• Jutta Heine (born 1940), German athlete
• Karl Heine (1819–1888), German lawyer and entrepreneur
• Karsten Heine (born 1955), German football player and manager
• Klaus Heine, German marketing lecturer
• Leina'ala Kalama Heine (died 2015), American kumu hula and hula instructor
• Max Heine (1911–1988), American investor and fund manager
• Maximilian Meyer Heine (1807–1879), German doctor and Russian state councilor
• Michel Heine (1819–1890), French banker and businessman
• Pete Heine (1928–2005), American politician
• Peter Heine (1928–2005), South African cricketer
• Robert von Heine-Geldern (1885–1968), Austrian ethnologist, historian, and archaeologist
• Salomon Heine (1767–1844), German merchant and banker
• Sara Heine (1858–1953), Russian-born Jewish actress
• Steven Heine (born 1950), American professor of religion and history
• Steven Heine (psychologist), Canadian professor
• Thomas Heine, Marshallese politician and government minister
• Thomas Theodor Heine (1867–1948), German painter and illustrator
• Veronika Heine (born 1986) Austrian table tennis player
• Vita Heine (born 1984), Latvian-Norwegian racing cyclist
• Volker Heine (born 1930), New Zealand-British physicist
• Werner Heine (1935–2022), German football player
• Wilbur Heine, Marshallese politician and government minister
• Wilhelm Heine (1827–1885), American painter and soldier
• William C. Heine (1911–1991), Canadian author and newspaper editor
• Wolfgang Heine (1861–1944), German jurist
• Yosef Heine, Israeli football player, active 1954–1964

• Heine Araújo (born 1984), Brazilian artistic gymnast
• Heinie Beau (1911–1987), American jazz composer and musician
• Heine Fernandez (born 1966), Danish football player
• Heine Havreki (1514–1576), Norwegian Lutheran pastor
• Heine Jensen (born 1977), Danish handball coach
• Heine Kanimea, Nauruan basketball player
• Heine Meine (1896–1968), American baseball player
• Heine Strathmann, German sprint canoeist, active in the late 1930s
• Heine Totland (born 1970), Norwegian singer
• Heine Wang (born 1963), Norwegian businessperson
• Herman Heine Goldstine (1913–2004), American mathematician and computer scientist
• Peter Heine Nielsen (born 1973), Danish chess player
• Veitel-Heine Ephraim (1703–1775), jeweller to the Prussian Court

• Heine Rammsteiner, protagonist in the Dogs: Bullets & Carnage manga
• Heine Westenfluss, a character in the anime television series Mobile Suit Gundam SEED
• Heine Wittgenstein, protagonist of the manga The Royal Tutor
• Heine, a character in the 2022 video game HARVESTELLA

• All pages with titles containing Heine
• Hein, a surname (including a list of people with the name)
• Heini, a given name and a surname (including a list of people with the name)
• Heyne, a surname (including a list of people with the name)
• Heines, a surname
• Hines (name), a name
• Hynes, a surname
• Heinie (disambiguation)