Protein-coding gene in the species Homo sapiens
Charged multivesicular body protein 1a is a protein that in humans is encoded by the CHMP1A gene .[5] [6] [7]
This gene encodes a member of the CHMP/Chmp family of proteins which are involved in multivesicular body sorting of proteins to the interiors of lysosomes. The initial prediction of the protein sequence encoded by this gene suggested that the encoded protein was a metallopeptidase. The nomenclature has been updated recently to reflect the correct biological function of this encoded protein.[7]
CHMP1A has been shown to interact with VPS4A .[5]
^ a b c GRCh38: Ensembl release 89: ENSG00000131165 – Ensembl , May 2017
^ a b c GRCm38: Ensembl release 89: ENSMUSG00000000743 – Ensembl , May 2017
^ "Human PubMed Reference:" . National Center for Biotechnology Information, U.S. National Library of Medicine .
^ "Mouse PubMed Reference:" . National Center for Biotechnology Information, U.S. National Library of Medicine .
^ a b Howard TL, Stauffer DR, Degnin CR, Hollenberg SM (July 2001). "CHMP1 functions as a member of a newly defined family of vesicle trafficking proteins" . Journal of Cell Science . 114 (Pt 13): 2395–404. doi :10.1242/jcs.114.13.2395 . PMID 11559748 .
^ Stauffer DR, Howard TL, Nyun T, Hollenberg SM (July 2001). "CHMP1 is a novel nuclear matrix protein affecting chromatin structure and cell-cycle progression" . Journal of Cell Science . 114 (Pt 13): 2383–93. doi :10.1242/jcs.114.13.2383 . PMID 11559747 .
^ a b "Entrez Gene: PCOLN3 procollagen (type III) N-endopeptidase" .
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