THC Science

ZNF644
Identifiers
Aliases	ZNF644, BM-005, MYP21, NatF, ZEP-2, zinc finger protein 644
External IDs	OMIM: 614159; MGI: 1277212; HomoloGene: 12971; GeneCards: ZNF644; OMA:ZNF644 - orthologs
Gene location (Human)
Chr.	Chromosome 1 (human)
End	91,022,272 bp
Gene location (Mouse)
Chr.	Chromosome 5 (mouse)
End	106,697,287 bp
RNA expression pattern
	Top expressed in
	Top expressed in
	More reference expression data
	n/a
Gene ontology
Molecular function
Cellular component
Biological process
	Sources:Amigo / QuickGO
Orthologs
	84146
	52397
	ENSG00000122482
	ENSMUSG00000049606
	Q9H582
	n/a
	NM_016620; NM_032186; NM_201269
NM_026856; NM_001363318; NM_001363319; NM_001363320; NM_001363321;
	NM_001363322; NM_001363323
	NP_057704; NP_115562; NP_958357
	n/a
	Wikidata
View/Edit Human	View/Edit Mouse

Zing finger protein 644 (ZNF644) also known as zinc finger motif enhancer-binding protein 2 (Zep-2) is a protein that in humans is encoded by the ZNF644 gene.^[5]

Clinical relevance

Mutations in the ZNF644 gene have been found in sporadic cases of high myopia.^[6]

References

^ ^a ^b ^c GRCh38: Ensembl release 89: ENSG00000122482 – Ensembl, May 2017
^ ^a ^b ^c GRCm38: Ensembl release 89: ENSMUSG00000049606 – Ensembl, May 2017
^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Entrez Gene: zinc finger protein 644".
^ Shi, Yi (2011). "Exome Sequencing Identifies ZNF644 Mutations in High Myopia". PLOS Genetics. 7 (6): e1002084. doi:10.1371/journal.pgen.1002084. PMC 3111487. PMID 21695231.

Zabaneh D, Balding DJ (2010). "A genome-wide association study of the metabolic syndrome in Indian Asian men". PLOS ONE. 5 (8): e11961. Bibcode:2010PLoSO...511961Z. doi:10.1371/journal.pone.0011961. PMC 2915922. PMID 20694148.
Mulligan P, Westbrook TF, Ottinger M, et al. (2008). "CDYL bridges REST and histone methyltransferases for gene repression and suppression of cellular transformation". Mol. Cell. 32 (5): 718–26. doi:10.1016/j.molcel.2008.10.025. PMC 6595072. PMID 19061646.
Beausoleil SA, Jedrychowski M, Schwartz D, et al. (2004). "Large-scale characterization of HeLa cell nuclear phosphoproteins". Proc. Natl. Acad. Sci. U.S.A. 101 (33): 12130–5. Bibcode:2004PNAS..10112130B. doi:10.1073/pnas.0404720101. PMC 514446. PMID 15302935.
Gregory SG, Barlow KF, McLay KE, et al. (2006). "The DNA sequence and biological annotation of human chromosome 1". Nature. 441 (7091): 315–21. Bibcode:2006Natur.441..315G. doi:10.1038/nature04727. PMID 16710414.
Zhang QH, Ye M, Wu XY, et al. (2000). "Cloning and functional analysis of cDNAs with open reading frames for 300 previously undefined genes expressed in CD34+ hematopoietic stem/progenitor cells". Genome Res. 10 (10): 1546–60. doi:10.1101/gr.140200. PMC 310934. PMID 11042152.

[refGRCh38Ensembl-1] GRCh38: Ensembl release 89: ENSG00000122482 – Ensembl, May 2017

[refGRCm38Ensembl-2] GRCm38: Ensembl release 89: ENSMUSG00000049606 – Ensembl, May 2017

[3] "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[4] "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[entrez-5] "Entrez Gene: zinc finger protein 644".

[6] Shi, Yi (2011). "Exome Sequencing Identifies ZNF644 Mutations in High Myopia". PLOS Genetics. 7 (6): e1002084. doi:10.1371/journal.pgen.1002084. PMC 3111487. PMID 21695231.

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