Cannabaceae

WMS-2539
Names
Preferred IUPAC name
(2S,4S)-2-[(4S)-2,2-Diphenyl-1,3-dioxolan-4-yl]-4-fluoropiperidine
Identifiers
3D model (JSmol)
ChEMBL
ChemSpider
  • InChI=1S/C20H22FNO2/c21-17-11-12-22-18(13-17)19-14-23-20(24-19,15-7-3-1-4-8-15)16-9-5-2-6-10-16/h1-10,17-19,22H,11-14H2/t17-,18-,19+/m0/s1
    Key: OLGOYYOHTNZCEO-GBESFXJTSA-N
  • InChI=1/C20H22FNO2/c21-17-11-12-22-18(13-17)19-14-23-20(24-19,15-7-3-1-4-8-15)16-9-5-2-6-10-16/h1-10,17-19,22H,11-14H2/t17-,18-,19+/m0/s1
    Key: OLGOYYOHTNZCEO-GBESFXJTBS
  • C1CN[C@@H](C[C@H]1F)[C@H]2COC(O2)(C3=CC=CC=C3)C4=CC=CC=C4
Properties
C20H22FNO2
Molar mass 327.399 g·mol−1
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).

WMS-2539 is a fluorinated derivative of dexoxadrol and a potent uncompetitive NMDA receptor antagonist.[1]

References

[edit]
  1. ^ Banerjee, A.; Schepmann, D.; Köhler, J.; Würthwein, E. U.; Wünsch, B. (2010). "Synthesis and SAR studies of chiral non-racemic dexoxadrol analogues as uncompetitive NMDA receptor antagonists". Bioorganic & Medicinal Chemistry. 18 (22): 7855–7867. doi:10.1016/j.bmc.2010.09.047. PMID 20965735.


One thought on “Cannabaceae

  1. Well, that’s interesting to know that Psilotum nudum are known as whisk ferns. Psilotum nudum is the commoner species of the two. While the P. flaccidum is a rare species and is found in the tropical islands. Both the species are usually epiphytic in habit and grow upon tree ferns. These species may also be terrestrial and grow in humus or in the crevices of the rocks.
    View the detailed Guide of Psilotum nudum: Detailed Study Of Psilotum Nudum (Whisk Fern), Classification, Anatomy, Reproduction

Leave a Reply