Names | |
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IUPAC name
Uridine 5′-(α-D-galactopyranosyl dihydrogen diphosphate)
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Systematic IUPAC name
O1-{[(2R,3S,4R,5R)-5-(2,4-Dioxo-3,4-dihydropyrimidin-1(2H)-yl)-3,4-dihydroxyoxolan-2-yl]methyl} O3-[(2R,3R,4S,5R,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl] dihydrogen diphosphate | |
Identifiers | |
3D model (JSmol)
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ChEMBL | |
ChemSpider | |
MeSH | Uridine+diphosphate+galactose |
PubChem CID
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UNII | |
CompTox Dashboard (EPA)
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Properties | |
C15H24N2O17P2 | |
Molar mass | 566.302 g/mol |
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
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Uridine diphosphate galactose (UDP-galactose) is an intermediate in the production of polysaccharides.[1] It is important in nucleotide sugars metabolism, and is the substrate for the transferase B4GALT5.
Sugar metabolism[edit]
UDP-Galactose is especially relevant in glycolysis. It is derived from galactose an epimer of glucose, and via the Leloir Pathway, it is used be used as a precursor for the metabolism of glucose into pyruvate.[2] When lactose is hydrolyzed, D-Galactose enters the liver via the bloodstream. There, galactokinase phosphorylates it to galactose-1-phosphate using ATP. This compound then engages in a "ping-pong" reaction with UDP-Glucose, catalyzed by uridylyltransferase, yielding glucose-1-phosphate and UDP-Galactose. This glucose-1-phosphate feeds into glycolysis, while UDP-Galactose undergoes epimerization to regenerate UDP-Glucose.[3]
See also[edit]
References[edit]
- ^ Los, E.; Ford, G. A. (2022). "Galactose 1 Phosphate Uridyltransferase Deficiency". StatPearls. StatPearls. PMID 28722986.
- ^ Garrett, Reginald H.; Grisham, Charles M. (2017). Biochemistry (6th ed.). Boston, MA, USA: Cengage Learning. ISBN 978-1-305-57720-6.
- ^ Nelson, David L.; Cox, Michael M.; Nelson, David L. (2013). Lehninger, Albert L. (ed.). Lehninger principles of biochemistry (6th ed.). Basingstoke: Macmillan Higher Education. ISBN 978-1-4292-3414-6.
Well, that’s interesting to know that Psilotum nudum are known as whisk ferns. Psilotum nudum is the commoner species of the two. While the P. flaccidum is a rare species and is found in the tropical islands. Both the species are usually epiphytic in habit and grow upon tree ferns. These species may also be terrestrial and grow in humus or in the crevices of the rocks.
View the detailed Guide of Psilotum nudum: Detailed Study Of Psilotum Nudum (Whisk Fern), Classification, Anatomy, Reproduction