Cannabaceae

Tilmacoxib
Pharmacokinetic data
Bioavailabilitysolution (64–88%) compared with capsule (22–40%).
Identifiers
  • 4-(4-cyclohexyl-2-methyl-1,3-oxazol-5-yl)-2-fluorobenzenesulfonamide
CAS Number
PubChem CID
ChemSpider
UNII
ChEBI
ChEMBL
CompTox Dashboard (EPA)
Chemical and physical data
FormulaC16H19FN2O3S
Molar mass338.40 g·mol−1
3D model (JSmol)
  • O=S(=O)(N)c3ccc(c1oc(nc1C2CCCCC2)C)cc3F
  • InChI=1S/C16H19FN2O3S/c1-10-19-15(11-5-3-2-4-6-11)16(22-10)12-7-8-14(13(17)9-12)23(18,20)21/h7-9,11H,2-6H2,1H3,(H2,18,20,21)
  • Key:MIMJSJSRRDZIPW-UHFFFAOYSA-N

Tilmacoxib or JTE-522 is a COX-2 inhibitor and is an effective chemopreventive agent against rat experimental liver fibrosis.[1]

See also

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References

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  1. ^ Yamamoto H, Kondo M, Nakamori S, Nagano H, Wakasa K, Sugita Y, et al. (August 2003). "JTE-522, a cyclooxygenase-2 inhibitor, is an effective chemopreventive agent against rat experimental liver fibrosis1". Gastroenterology. 125 (2): 556–71. doi:10.1016/s0016-5085(03)00904-1. PMID 12891558.

One thought on “Cannabaceae

  1. Well, that’s interesting to know that Psilotum nudum are known as whisk ferns. Psilotum nudum is the commoner species of the two. While the P. flaccidum is a rare species and is found in the tropical islands. Both the species are usually epiphytic in habit and grow upon tree ferns. These species may also be terrestrial and grow in humus or in the crevices of the rocks.
    View the detailed Guide of Psilotum nudum: Detailed Study Of Psilotum Nudum (Whisk Fern), Classification, Anatomy, Reproduction

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