Cannabaceae

Thyrotoxicosis factitia
SpecialtyEndocrinology

Thyrotoxicosis factitia (alimentary thyrotoxicosis, exogenous thyrotoxicosis)[1][2] is a condition of thyrotoxicosis caused by the ingestion[3] of exogenous thyroid hormone.[4][5] It can be the result of mistaken ingestion of excess drugs, such as levothyroxine[6] and triiodothyronine,[7] or as a symptom of Munchausen syndrome. It is an uncommon form of hyperthyroidism.

Patients present with hyperthyroidism and may be mistaken for Graves’ disease, if TSH receptor positive, or thyroiditis because of absent uptake on a thyroid radionuclide uptake scan due to suppression of thyroid function by exogenous thyroid hormones.[8] Ingestion of thyroid hormone also suppresses thyroglobulin levels helping to differentiate thyrotoxicosis factitia from other causes of hyperthyroidism, in which serum thyroglobulin is elevated. Caution, however, should be exercised in interpreting thyroglobulin results without thyroglobulin antibodies, since thyroglobulin antibodies commonly interfere in thyroglobulin immunoassays causing false positive and negative results which may lead to clinical misdirection. In such cases, increased fecal thyroxine levels in thyrotoxicosis factitia may help differentiate it from other causes of hyperthyroidism.[citation needed]

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References[edit]

  1. ^ Mathioudakis N., Cooper D.S. (2015) Exogenous Thyrotoxicosis. In: Davies T. (eds) A Case-Based Guide to Clinical Endocrinology. Springer, New York, NY
  2. ^ Lucie Wartique, Lucie Pothen, Nathalie Pirson, Michel P. Hermans, Michel Lambert & Halil Yildiz (2017) An unusual cause of epidemic thyrotoxicosis. In: Acta Clinica Belgica, 72:6, 451–453, DOI: 10.1080/17843286.2017.1309336
  3. ^ "Hamburger Thyrotoxicosis". www.vivo.colostate.edu.
  4. ^ Vaidya, B; Pearce, S. H. S (2014). "Diagnosis and management of thyrotoxicosis". BMJ. 349: g5128. doi:10.1136/bmj.g5128. PMC 1476727. PMID 25146390.
  5. ^ Pearce EN: Diagnosis and management of thyrotoxicosis. In: BMJ. 2006 Jun 10; 332(7554): 1369–1373.
  6. ^ Geraldo Medeiros-Neto: Thyroxine Poisoning. in: Endotext, Created: July 17, 2018.
  7. ^ Kang GY et al.: Thyroxine and triiodothyronine content in commercially available thyroid health supplements. In: Thyroid. 2013 Oct; 23(10): 1233-1237.
  8. ^ Jahagirdar, V R; Strouhal, P; Holder, G; Gama, R; Singh, B M (2008). "Thyrotoxicosis factitia masquerading as recurrent Graves' disease: Endogenous antibody immunoassay interference, a pitfall for the unwary". Annals of Clinical Biochemistry. 45 (3): 325–327. doi:10.1258/acb.2007.007163. PMID 18482926. S2CID 34751194.

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One thought on “Cannabaceae

  1. Well, that’s interesting to know that Psilotum nudum are known as whisk ferns. Psilotum nudum is the commoner species of the two. While the P. flaccidum is a rare species and is found in the tropical islands. Both the species are usually epiphytic in habit and grow upon tree ferns. These species may also be terrestrial and grow in humus or in the crevices of the rocks.
    View the detailed Guide of Psilotum nudum: Detailed Study Of Psilotum Nudum (Whisk Fern), Classification, Anatomy, Reproduction

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