For the TCF1 gene, see
HNF1A .
Protein-coding gene in the species Homo sapiens
Transcription factor 7 is the gene that in humans encodes for the TCF1 protein .[5]
References [ edit ] Further reading [ edit ]
van de Wetering M, Oosterwegel M, Holstege F, et al. (1992). "The human T cell transcription factor-1 gene. Structure, localization, and promoter characterization" . J. Biol. Chem . 267 (12): 8530–6. doi :10.1016/S0021-9258(18)42476-3 PMID 1569101 . van de Wetering M, Oosterwegel M, Dooijes D, Clevers H (1991). "Identification and cloning of TCF-1, a T lymphocyte-specific transcription factor containing a sequence-specific HMG box" . EMBO J . 10 (1): 123–32. doi :10.1002/j.1460-2075.1991.tb07928.x . PMC 452620 PMID 1989880 . Castrop J, van Wichen D, Koomans-Bitter M, et al. (1995). "The human TCF-1 gene encodes a nuclear DNA-binding protein uniquely expressed in normal and neoplastic T-lineage lymphocytes" . Blood . 86 (8): 3050–9. doi :10.1182/blood.V86.8.3050.3050 hdl :20.500.11755/05a0e0d7-f80c-4035-a8da-056c8b5b7883 PMID 7579399 . Mayer K, Wolff E, Clevers H, Ballhausen WG (1995). "The human high mobility group (HMG)-box transcription factor TCF-1: novel isoforms due to alternative splicing and usage of a new exon IXA". Biochim. Biophys. Acta . 1263 (2): 169–72. doi :10.1016/0167-4781(95)00108-s . PMID 7640309 . Van de Wetering M, Castrop J, Korinek V, Clevers H (1996). "Extensive alternative splicing and dual promoter usage generate Tcf-1 protein isoforms with differential transcription control properties" . Mol. Cell. Biol . 16 (3): 745–52. doi :10.1128/mcb.16.3.745 . PMC 231054 PMID 8622675 . Korinek V, Barker N, Willert K, et al. (1998). "Two members of the Tcf family implicated in Wnt/beta-catenin signaling during embryogenesis in the mouse" . Mol. Cell. Biol . 18 (3): 1248–56. doi :10.1128/MCB.18.3.1248 . PMC 108837 PMID 9488439 . Roose J, Molenaar M, Peterson J, et al. (1998). "The Xenopus Wnt effector XTcf-3 interacts with Groucho-related transcriptional repressors". Nature . 395 (6702): 608–12. Bibcode :1998Natur.395..608R . doi :10.1038/26989 . PMID 9783587 . S2CID 4347003 . Roose J, Huls G, van Beest M, et al. (1999). "Synergy between tumor suppressor APC and the beta-catenin-Tcf4 target Tcf1". Science . 285 (5435): 1923–6. doi :10.1126/science.285.5435.1923 . PMID 10489374 . Brantjes H, Roose J, van De Wetering M, Clevers H (2001). "All Tcf HMG box transcription factors interact with Groucho-related co-repressors" . Nucleic Acids Res . 29 (7): 1410–9. doi :10.1093/nar/29.7.1410 . PMC 31284 PMID 11266540 . Batlle E, Henderson JT, Beghtel H, et al. (2002). "Beta-catenin and TCF mediate cell positioning in the intestinal epithelium by controlling the expression of EphB/ephrinB" . Cell . 111 (2): 251–63. doi :10.1016/S0092-8674(02)01015-2 PMID 12408869 . S2CID 10103038 . Noble JA, White AM, Lazzeroni LC, et al. (2003). "A polymorphism in the TCF7 gene, C883A, is associated with type 1 diabetes" . Diabetes . 52 (6): 1579–82. doi :10.2337/diabetes.52.6.1579 PMID 12765974 . Ioannidis V, Kunz B, Tanamachi DM, et al. (2003). "Initiation and limitation of Ly-49A NK cell receptor acquisition by T cell factor-1" . J. Immunol . 171 (2): 769–75. doi :10.4049/jimmunol.171.2.769 PMID 12847244 . Smit L, Baas A, Kuipers J, et al. (2004). "Wnt activates the Tak1/Nemo-like kinase pathway" . J. Biol. Chem . 279 (17): 17232–40. doi :10.1074/jbc.M307801200 PMID 14960582 . Smith SS, Patterson T, Pauza ME (2005). "Transgenic Ly-49A inhibits antigen-driven T cell activation and delays diabetes" . J. Immunol . 174 (7): 3897–905. doi :10.4049/jimmunol.174.7.3897 PMID 15778344 . Willinger T, Freeman T, Herbert M, et al. (2006). "Human naive CD8 T cells down-regulate expression of the WNT pathway transcription factors lymphoid enhancer binding factor 1 and transcription factor 7 (T cell factor-1) following antigen encounter in vitro and in vivo" . J. Immunol . 176 (3): 1439–46. doi :10.4049/jimmunol.176.3.1439 hdl :20.500.11820/b4e3a221-e38b-4f3a-9dbe-1641533de25a PMID 16424171 .
(1) Basic domains
(1.1) Basic leucine zipper (bZIP )(1.2) Basic helix-loop-helix (bHLH )
Group A Group B Group CPAS Group D Group E Group F
(1.3) bHLH-ZIP (1.4) NF-1 (1.5) RF-X (1.6) Basic helix-span-helix (bHSH)
(2) Zinc finger DNA-binding domains
(2.1) Nuclear receptor (Cys4 )
subfamily 1 subfamily 2 subfamily 3 subfamily 4 subfamily 5 subfamily 6 subfamily 0
(2.2) Other Cys4 (2.3) Cys2 His2 (2.4) Cys6 (2.5) Alternating composition (2.6) WRKY
(4) β-Scaffold factors with minor groove contacts
(0) Other transcription factors
Well, that’s interesting to know that Psilotum nudum are known as whisk ferns. Psilotum nudum is the commoner species of the two. While the P. flaccidum is a rare species and is found in the tropical islands. Both the species are usually epiphytic in habit and grow upon tree ferns. These species may also be terrestrial and grow in humus or in the crevices of the rocks.
View the detailed Guide of Psilotum nudum: Detailed Study Of Psilotum Nudum (Whisk Fern), Classification, Anatomy, Reproduction