Cannabaceae

Renanolone
Clinical data
ATC code
  • none
Identifiers
  • 3α-hydroxy-5β-pregnane-11,20-dione
CAS Number
PubChem CID
ChemSpider
UNII
CompTox Dashboard (EPA)
Chemical and physical data
FormulaC20H30O4
Molar mass334.456 g·mol−1
3D model (JSmol)
  • CC(=O)[C@H]1CC[C@H]2[C@@H]3CC[C@@H]4C[C@H](O)CC[C@]4(O)[C@H]3C(=O)C[C@]12C
  • InChI=1S/C20H30O4/c1-11(21)15-5-6-16-14-4-3-12-9-13(22)7-8-20(12,24)18(14)17(23)10-19(15,16)2/h12-16,18,22,24H,3-10H2,1-2H3/t12-,13-,14+,15-,16+,18-,19-,20-/m1/s1
  • Key:ICICFVFEPDWWAQ-MNYWXNLXSA-N

Renanolone (INN), or 11-ketopregnanolone, also known as 5β-pregnan-3α-ol-11,20-dione, is a synthetic[citation needed] neuroactive steroid which is described as a general anesthetic but was never introduced for clinical use.[1] Its isomers, alfaxolone and alfadolone, are also general anesthetics, and are known to act as positive allosteric modulators of the GABAA receptor, a property which is likely the case for renanolone as well.

Chemistry[edit]

See also[edit]

References[edit]

  1. ^ Hill RA, Makin HL, Kirk DN, Murphy GM (23 May 1991). Dictionary of Steroids. CRC Press. p. 592. ISBN 978-0-412-27060-4.



One thought on “Cannabaceae

  1. Well, that’s interesting to know that Psilotum nudum are known as whisk ferns. Psilotum nudum is the commoner species of the two. While the P. flaccidum is a rare species and is found in the tropical islands. Both the species are usually epiphytic in habit and grow upon tree ferns. These species may also be terrestrial and grow in humus or in the crevices of the rocks.
    View the detailed Guide of Psilotum nudum: Detailed Study Of Psilotum Nudum (Whisk Fern), Classification, Anatomy, Reproduction

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