The protein encoded by this gene belongs to the small GTPase superfamily, Rab family. It is associated with both constitutive and regulated secretory pathways, and may be involved in protein transport.[7]
Rab-11a controls intracellular trafficking of the innate immunereceptorTLR4, and thereby also receptor signaling[8]
^"Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^"Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^Drivas GT, Shih A, Coutavas EE, D'Eustachio P, Rush MG (January 1991). "Identification and characterization of a human homolog of the Schizosaccharomyces pombe ras-like gene YPT-3". Oncogene. 6 (1): 3–9. PMID1704119.
^Ewing RM, Chu P, Elisma F, Li H, Taylor P, Climie S, McBroom-Cerajewski L, Robinson MD, O'Connor L, Li M, Taylor R, Dharsee M, Ho Y, Heilbut A, Moore L, Zhang S, Ornatsky O, Bukhman YV, Ethier M, Sheng Y, Vasilescu J, Abu-Farha M, Lambert JP, Duewel HS, Stewart II, Kuehl B, Hogue K, Colwill K, Gladwish K, Muskat B, Kinach R, Adams SL, Moran MF, Morin GB, Topaloglou T, Figeys D (2007). "Large-scale mapping of human protein-protein interactions by mass spectrometry". Molecular Systems Biology. 3: 89. doi:10.1038/msb4100134. PMC1847948. PMID17353931.
^Wallace DM, Lindsay AJ, Hendrick AG, McCaffrey MW (December 2002). "Rab11-FIP4 interacts with Rab11 in a GTP-dependent manner and its overexpression condenses the Rab11 positive compartment in HeLa cells". Biochemical and Biophysical Research Communications. 299 (5): 770–9. doi:10.1016/s0006-291x(02)02720-1. PMID12470645.
Sakurada K, Uchida K, Yamaguchi K, Aisaka K, Ito S, Ohmori T, Takeyama Y, Ueda T, Hori Y, Ohyanagi H (June 1991). "Molecular cloning and characterization of a ras p21-like GTP-binding protein (24KG) from rat liver". Biochemical and Biophysical Research Communications. 177 (3): 1224–32. doi:10.1016/0006-291X(91)90672-T. PMID1711847.
Shisheva A, Chinni SR, DeMarco C (September 1999). "General role of GDP dissociation inhibitor 2 in membrane release of Rab proteins: modulations of its functional interactions by in vitro and in vivo structural modifications". Biochemistry. 38 (36): 11711–21. doi:10.1021/bi990200r. PMID10512627.
1oiv: X-RAY STRUCTURE OF THE SMALL G PROTEIN RAB11A IN COMPLEX WITH GDP
1oiw: X-RAY STRUCTURE OF THE SMALL G PROTEIN RAB11A IN COMPLEX WITH GTPGAMMAS
1oix: X-RAY STRUCTURE OF THE SMALL G PROTEIN RAB11A IN COMPLEX WITH GDP AND PI
1yzk: GppNHp bound Rab11 GTPase
2d7c: Crystal structure of human Rab11 in complex with FIP3 Rab-binding domain
2f9l: 3D structure of inactive human Rab11b GTPase
2f9m: 3D structure of active human Rab11b GTPase
2gzd: Crystal Structure of Rab11 in Complex with Rab11-FIP2
2gzh: Crystal Structure of Rab11 in Complex with Rab11-Family Interacting Protein 2
2hv8: Crystal structure of GTP-bound Rab11 in complex with FIP3
One thought on “Cannabaceae”
Well, that’s interesting to know that Psilotum nudum are known as whisk ferns. Psilotum nudum is the commoner species of the two. While the P. flaccidum is a rare species and is found in the tropical islands. Both the species are usually epiphytic in habit and grow upon tree ferns. These species may also be terrestrial and grow in humus or in the crevices of the rocks.
View the detailed Guide of Psilotum nudum: Detailed Study Of Psilotum Nudum (Whisk Fern), Classification, Anatomy, Reproduction
Well, that’s interesting to know that Psilotum nudum are known as whisk ferns. Psilotum nudum is the commoner species of the two. While the P. flaccidum is a rare species and is found in the tropical islands. Both the species are usually epiphytic in habit and grow upon tree ferns. These species may also be terrestrial and grow in humus or in the crevices of the rocks.
View the detailed Guide of Psilotum nudum: Detailed Study Of Psilotum Nudum (Whisk Fern), Classification, Anatomy, Reproduction