| PrfA thermoregulator UTR | |
|---|---|
 Predicted secondary structure and sequence conservation of PrfA | |
| Identifiers | |
| Symbol | PrfA |
| Rfam | RF00038 |
| Other data | |
| RNA type | Cis-reg; thermoregulator |
| Domain(s) | Bacteria |
| SO | SO:0000233 |
| PDB structures | PDBe |
The PrfA thermoregulator UTR is an RNA thermometer found in the 5' UTR of the prfA gene.[1] In Listeria monocytogenes, virulence genes are maximally expressed at 37 °C (human body temperature) but are almost silent at 30 °C.[2] The genes are controlled by PrfA, a transcriptional activator whose expression is thermoregulated.[3] It has been shown that the untranslated mRNA (UTR) preceding prfA, forms a secondary structure, which masks the ribosome binding region.[1] It is thought that at 37 °C, the hairpin structure 'melts' and the SD sequence is unmasked.[1]
References
[edit]- ^ a b c Johansson J, Mandin P, Renzoni A, Chiaruttini C, Springer M, Cossart P (2002). "An RNA thermosensor controls expression of virulence genes in Listeria monocytogenes". Cell. 110 (5): 551–561. doi:10.1016/S0092-8674(02)00905-4. PMID 12230973.
- ^ Freitag, NE; Port, GC; Miner, MD (September 2009). "Listeria monocytogenes - from saprophyte to intracellular pathogen". Nature Reviews. Microbiology. 7 (9): 623–628. doi:10.1038/nrmicro2171. PMC 2813567. PMID 19648949.
- ^ Digel, I; Kayser, P; Artmann, GM (2008). "Molecular processes in biological thermosensation". Journal of Biophysics. 2008: 602870. doi:10.1155/2008/602870. PMC 2814129. PMID 20130806.
Well, that’s interesting to know that Psilotum nudum are known as whisk ferns. Psilotum nudum is the commoner species of the two. While the P. flaccidum is a rare species and is found in the tropical islands. Both the species are usually epiphytic in habit and grow upon tree ferns. These species may also be terrestrial and grow in humus or in the crevices of the rocks.
View the detailed Guide of Psilotum nudum: Detailed Study Of Psilotum Nudum (Whisk Fern), Classification, Anatomy, Reproduction