Cannabaceae

Pipoxizine
Clinical data
ATC code
  • None
Identifiers
  • 2-(2-{2-[4-(Diphenylmethylene)-1-piperidinyl]ethoxy}ethoxy)ethanol
CAS Number
PubChem CID
ChemSpider
UNII
Chemical and physical data
FormulaC24H31NO3
Molar mass381.516 g·mol−1
3D model (JSmol)
  • c1ccc(cc1)C(=C2CCN(CC2)CCOCCOCCO)c3ccccc3
  • InChI=1S/C24H31NO3/c26-16-18-28-20-19-27-17-15-25-13-11-23(12-14-25)24(21-7-3-1-4-8-21)22-9-5-2-6-10-22/h1-10,26H,11-20H2
  • Key:SCMPXORBOTWFTI-UHFFFAOYSA-N

Pipoxizine (INNTooltip International Nonproprietary Name) is a first-generation antihistamine as well as serotonin antagonist of the diphenylmethylpiperazine group related to hydroxyzine.[1][2] It was investigated as a bronchodilator but was never marketed.[1][3][4]

References[edit]

  1. ^ a b Ganellin CR, Triggle DJ (21 November 1996). Dictionary of Pharmacological Agents. CRC Press. pp. 1619–. ISBN 978-0-412-46630-4.
  2. ^ World Health Organization (1988). International Nonproprietary Names (INN) for Pharmaceutical Substances. W.H.O. ISBN 9789240560369.
  3. ^ Brunner A, Gartmann J, Studler H. "Pipoxizine, a New Bronchodilator". Lung. 154 (2): 143.
  4. ^ Neukirch F, Korobaeff M, Verdier F, Timsit G, Fay M, Drutel P (1978). "[Effect of a histamine aerosol in 20 subjects with histamine hyperreactivity. Application to a study of the protective properties of pipoxizine]". Revue de l'Institut d'Hygiene des Mines (in French). 33 (4): 191–195. PMID 45187.

One thought on “Cannabaceae

  1. Well, that’s interesting to know that Psilotum nudum are known as whisk ferns. Psilotum nudum is the commoner species of the two. While the P. flaccidum is a rare species and is found in the tropical islands. Both the species are usually epiphytic in habit and grow upon tree ferns. These species may also be terrestrial and grow in humus or in the crevices of the rocks.
    View the detailed Guide of Psilotum nudum: Detailed Study Of Psilotum Nudum (Whisk Fern), Classification, Anatomy, Reproduction

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