Cannabaceae

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Pinoxepin
Clinical data
Other namesPinoxepine; P-5227
Routes of
administration		Oral
Identifiers
  • 2-[4-[(3Z)-3-(2-Chloro-6H-benzo[c][1]benzoxepin-11-ylidene)propyl]piperazin-1-yl]ethanol
CAS Number
PubChem CID
ChemSpider
UNII
ChEMBL
CompTox Dashboard (EPA)
Chemical and physical data
FormulaC23H27ClN2O2
Molar mass398.93 g·mol−1
3D model (JSmol)
  • C1CN(CCN1CC/C=C\2/C3=CC=CC=C3COC4=C2C=C(C=C4)Cl)CCO
  • InChI=1S/C23H27ClN2O2/c24-19-7-8-23-22(16-19)21(20-5-2-1-4-18(20)17-28-23)6-3-9-25-10-12-26(13-11-25)14-15-27/h1-2,4-8,16,27H,3,9-15,17H2/b21-6-
  • Key:RAAHIUIRJUOMAU-MPUCSWFWSA-N

Pinoxepin (INNTooltip International Nonproprietary Name; developmental code name P-5227; pinoxepin hydrochloride (USANTooltip United States Adopted Name)) is an antipsychotic of the tricyclic group with a dibenzoxepin ring system which was developed in the 1960s but was never marketed.[1][2][3][4][5] It was found in clinical trials to have effectiveness in the treatment of schizophrenia similar to that of chlorpromazine and thioridazine.[4] The drug has marked sedative effects but causes relatively mild extrapyramidal symptoms.[2][4]

References[edit]

  1. ^ Elks J (14 November 2014). The Dictionary of Drugs: Chemical Data: Chemical Data, Structures and Bibliographies. Springer. pp. 984–. ISBN 978-1-4757-2085-3.
  2. ^ a b Annual Reports in Medicinal Chemistry. Academic Press. 1 January 1967. pp. 2–. ISBN 978-0-08-058346-4.
  3. ^ Gordon M (2 December 2012). Psychopharmacological Agents. Elsevier Science. pp. 102–. ISBN 978-0-323-15128-3.
  4. ^ a b c Iversen L (6 December 2012). Handbook of Psychopharmacology: Volume 10: Neoroleptics and Schizophrenia. Springer Science & Business Media. pp. 200–. ISBN 978-1-4613-4042-3.
  5. ^ Lajtha A (11 November 2013). Alterations of Metabolites in the Nervous System. Springer Science & Business Media. pp. 335–. ISBN 978-1-4757-6740-7.



source: https://en.wikipedia.org/wiki/Pinoxepin

One thought on “Cannabaceae”

  1. Well, that’s interesting to know that Psilotum nudum are known as whisk ferns. Psilotum nudum is the commoner species of the two. While the P. flaccidum is a rare species and is found in the tropical islands. Both the species are usually epiphytic in habit and grow upon tree ferns. These species may also be terrestrial and grow in humus or in the crevices of the rocks.
    View the detailed Guide of Psilotum nudum: Detailed Study Of Psilotum Nudum (Whisk Fern), Classification, Anatomy, Reproduction

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