Cannabaceae

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Pindone
Names
Preferred IUPAC name
2-(2,2-Dimethylpropanoyl)-1H-indene-1,3(2H)-dione
Other names
2-Pivaloyl-1,3-indandione
Identifiers
3D model (JSmol)
ChemSpider
ECHA InfoCard 100.001.330 Edit this at Wikidata
KEGG
UNII
  • InChI=1S/C14H14O3/c1-14(2,3)13(17)10-11(15)8-6-4-5-7-9(8)12(10)16/h4-7,10H,1-3H3 checkY
    Key: RZKYEQDPDZUERB-UHFFFAOYSA-N checkY
  • InChI=1/C14H14O3/c1-14(2,3)13(17)10-11(15)8-6-4-5-7-9(8)12(10)16/h4-7,10H,1-3H3
    Key: RZKYEQDPDZUERB-UHFFFAOYAX
  • O=C2c1ccccc1C(=O)C2C(=O)C(C)(C)C
Properties
C14H14O3
Molar mass 230.26 g/mol
Appearance Bright-yellow powder[1]
Odor almost none
Density 1.06 g/mL
Melting point 110 °C (230 °F; 383 K)
0.002% (25°C)[1]
Hazards
Lethal dose or concentration (LD, LC):
280 mg/kg (rat, oral)
75 mg/kg (dog, oral)
150 mg/kg (rabbit, oral)[2]
NIOSH (US health exposure limits):
PEL (Permissible)
 TWA 0.1 mg/m3[1]
REL (Recommended)
 TWA 0.1 mg/m3[1]
IDLH (Immediate danger)
 100 mg/m3[1]
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
☒N verify (what is checkY☒N ?)

Pindone is an anticoagulant drug[3] for agricultural use. It is commonly used as a rodenticide in the management of rat and rabbit populations.

It is pharmacologically analogous to warfarin and inhibits the synthesis of Vitamin K-dependent clotting factors.

See also[edit]

References[edit]

  1. ^ a b c d e NIOSH Pocket Guide to Chemical Hazards. "#0516". National Institute for Occupational Safety and Health (NIOSH).
  2. ^ "Pindone". Immediately Dangerous to Life or Health Concentrations (IDLH). National Institute for Occupational Safety and Health (NIOSH).
  3. ^ Robinson MH, Twigg LE, Wheeler SH, Martin GR (March 2005). "Effect of the anticoagulant, pindone, on the breeding performance and survival of merino sheep, Ovis aries". Comp. Biochem. Physiol. B. 140 (3): 465–73. doi:10.1016/j.cbpc.2004.11.011. PMID 15694595.


source: https://en.wikipedia.org/wiki/Pindone

One thought on “Cannabaceae”

  1. Well, that’s interesting to know that Psilotum nudum are known as whisk ferns. Psilotum nudum is the commoner species of the two. While the P. flaccidum is a rare species and is found in the tropical islands. Both the species are usually epiphytic in habit and grow upon tree ferns. These species may also be terrestrial and grow in humus or in the crevices of the rocks.
    View the detailed Guide of Psilotum nudum: Detailed Study Of Psilotum Nudum (Whisk Fern), Classification, Anatomy, Reproduction

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