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| Identifiers | |||||||||||||||||||||||||||||||||||||||||||||||||||
| Aliases | PMVK, HUMPMKI, PMK, PMKA, PMKASE, POROK1, phosphomevalonate kinase | ||||||||||||||||||||||||||||||||||||||||||||||||||
| External IDs | OMIM: 607622; MGI: 1915853; HomoloGene: 4779; GeneCards: PMVK; OMA:PMVK - orthologs | ||||||||||||||||||||||||||||||||||||||||||||||||||
| EC number | 2.7.4.2 | ||||||||||||||||||||||||||||||||||||||||||||||||||
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| Phosphomevalonate kinase | |||||||||
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| Identifiers | |||||||||
| EC no. | 2.7.4.2 | ||||||||
| CAS no. | 9026-46-4 | ||||||||
| Databases | |||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB structures | RCSB PDB PDBe PDBsum | ||||||||
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| Phosphomevalonate kinase | |||||||
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| Identifiers | |||||||
| Symbol | PMVK | ||||||
| NCBI gene | 10654 | ||||||
| HGNC | 9141 | ||||||
| OMIM | 607622 | ||||||
| RefSeq | NM_006556 | ||||||
| UniProt | Q15126 | ||||||
| Other data | |||||||
| EC number | 2.7.4.2 | ||||||
| Locus | Chr. 1 p13-q23 | ||||||
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Phosphomevalonate kinase is an enzyme (EC 2.7.4.2) in the mevalonate pathway[5][6][7] that in humans is encoded by the PMVK gene.
References[edit]
- ^ a b c GRCh38: Ensembl release 89: ENSG00000163344 – Ensembl, May 2017
- ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000027952 – Ensembl, May 2017
- ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
- ^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
- ^ Bloch K, Chaykin S, Phillips AH, De Waard A (October 1959). "Mevalonic acid pyrophosphate and isopentenylpyrophosphate". The Journal of Biological Chemistry. 234 (10): 2595–604. doi:10.1016/S0021-9258(18)69744-3. PMID 13801508.
- ^ Henning U, Moslein EM, Lynen F (July 1959). "Biosynthesis of terpenes. V. Formation of 5-pyrophosphomevalonic acid by phosphomevalonic kinase". Archives of Biochemistry and Biophysics. 83 (1): 259–67. doi:10.1016/0003-9861(59)90031-1. PMID 13662013.
- ^ Levy HR, Popjak G (June 1960). "Studies on the biosynthesis of cholesterol. 10. Mevalonic kinase from liver". The Biochemical Journal. 75 (3): 417–28. doi:10.1042/bj0750417. PMC 1204488. PMID 14416398.
External links[edit]
- Phosphomevalonate+kinase at the U.S. National Library of Medicine Medical Subject Headings (MeSH)
- Overview of all the structural information available in the PDB for UniProt: Q15126 (Phosphomevalonate kinase) at the PDBe-KB.
Well, that’s interesting to know that Psilotum nudum are known as whisk ferns. Psilotum nudum is the commoner species of the two. While the P. flaccidum is a rare species and is found in the tropical islands. Both the species are usually epiphytic in habit and grow upon tree ferns. These species may also be terrestrial and grow in humus or in the crevices of the rocks.
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