Names | |
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IUPAC name
Polyethylene glycol
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Identifiers | |
ChemSpider |
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UNII | |
Properties | |
C2nH4n+2On+1, n = 8.2 to 9.1 | |
Molar mass | 380-420 g/mol |
Density | 1.128 g/cm3 |
Melting point | 4 to 8 °C (39 to 46 °F; 277 to 281 K) |
Viscosity | 90.0 cSt at 25 °C, 7.3 cSt at 99 °C |
Hazards | |
Flash point | 238 °C (460 °F; 511 K) |
Lethal dose or concentration (LD, LC): | |
LD50 (median dose)
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30 mL/kg, orally in rats |
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
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PEG 400 (polyethylene glycol 400) is a low-molecular-weight grade of polyethylene glycol. It is a clear, colorless, viscous liquid. Due in part to its low toxicity, PEG 400 is widely used in a variety of pharmaceutical formulations.
Chemical properties[edit]
PEG 400 is strongly hydrophilic. The partition coefficient of PEG 400 between hexane and water is 0.000015 (log), indicating that when PEG 400 is mixed with water and hexane, there are only 15 parts of PEG400 in the hexane layer per 1 million parts of PEG 400 in the water layer.[1]
PEG 400 is soluble in water, acetone, alcohols, benzene, glycerin, glycols, and aromatic hydrocarbons. It is not miscible with aliphatic hydrocarbons and diethyl ether. Therefore, reaction products can be extracted from the reaction media with those solvents.
References[edit]
- ^ T. Y. Ma; D. Hollander; P. Krugliak; K. Katz (1990). "PEG 400, a hydrophilic molecular probe for measuring intestinal permeability". Gastroenterology. 98 (1): 39–46. doi:10.1016/0016-5085(90)91288-h. PMID 2293598.
- The Merck Index, 11th Edition
- Handbook of Pharmaceutical Excipients
Well, that’s interesting to know that Psilotum nudum are known as whisk ferns. Psilotum nudum is the commoner species of the two. While the P. flaccidum is a rare species and is found in the tropical islands. Both the species are usually epiphytic in habit and grow upon tree ferns. These species may also be terrestrial and grow in humus or in the crevices of the rocks.
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