Orthopoxvirus inclusion bodies are aggregates of stainable protein produced by poxvirus virions in the cell nuclei and/or cytoplasm of epithelial cells in humans. They are important as sites of viral replication.[1][2]
Morphology
[edit]Morphologically there are two types of Orthopoxvirus inclusion bodies, Type-A inclusion bodies and Guarnieri bodies. Type-A inclusion bodies are found only in certain poxviruses like cowpox.[3] The Guarnieri bodies are found in all poxvirus infections and their presence is diagnostic.[4] The diagnosis of an orthopoxvirus infection can also be made rapidly by electron microscopic examination of pustular fluid or scabs. However, all orthopoxviruses exhibit identical brick-shaped virions by electron microscopy.[citation needed]
Guarnieri bodies are named for Giuseppe Guarnieri, (1856-1918) an Italian physician who first described them.[5]
References
[edit]- ^ Howard, AR; Moss, B (May 2012). "Formation of orthopoxvirus cytoplasmic A-type inclusion bodies and embedding of virions are dynamic processes requiring microtubules". J Virol. 86 (10): 5905–14. doi:10.1128/JVI.06997-11. PMC 3347259. PMID 22438543.
- ^ Fenner, F., Witte, K.R., and Dumbell, K.R. The Orthopoxviruses. Academic Press, San Diego, 1989.
- ^ Leite, JA; da Fonseca, FG; de Souza Trindade, G; Abrahão, JS; Arantes, RM; de Almeida-Leite, CM; Santos, JR; Guedes, MI; Ribeiro, BM; Bonjardim, CA; Ferreira, PC; Kroon, EG (Apr 2011). "A-type inclusion bodies: a factor influencing cowpox virus lesion pathogenesis". Arch Virol. 156 (4): 617–28. doi:10.1007/s00705-010-0900-0. PMID 21212997. S2CID 33135261.
- ^ Riedel S (January 2005). "Smallpox and biological warfare: a disease revisited". Proc (Bayl Univ Med Cent). 18 (1): 13–20. doi:10.1080/08998280.2005.11928026. PMC 1200695. PMID 16200143.
- ^ Forbis, Pat; Bartolucci, Susan L.; Stedman, Thomas Lathrop (2005). Stedman's medical eponyms. Hagerstwon, MD: Lippincott Williams & Wilkins. p. 294. ISBN 0-7817-5443-7.
Well, that’s interesting to know that Psilotum nudum are known as whisk ferns. Psilotum nudum is the commoner species of the two. While the P. flaccidum is a rare species and is found in the tropical islands. Both the species are usually epiphytic in habit and grow upon tree ferns. These species may also be terrestrial and grow in humus or in the crevices of the rocks.
View the detailed Guide of Psilotum nudum: Detailed Study Of Psilotum Nudum (Whisk Fern), Classification, Anatomy, Reproduction