Cannabaceae

ω-Atracotoxin
Identifiers
SymbolOmega-toxin
PfamPF06357
InterProIPR009415
SCOP21hvw / SCOPe / SUPFAM
Available protein structures:
Pfam  structures / ECOD  
PDBRCSB PDB; PDBe; PDBj
PDBsumstructure summary
PDB1hvwA:4-23 1axh :1-37

omega-Atracotoxin (ω-atracotoxin) is an insect-specific neurotoxin produced by the Blue Mountains funnel-web spider. Its phylogenetic specificity derives from its ability to antagonise insect, but not vertebrate, voltage-gated calcium channels. Two spatially proximal amino acid residues, Asn(27) and Arg(35), form a contiguous molecular surface that is essential for toxin activity. It has been proposed that this surface of the beta-hairpin is a key site for interaction of the toxin with insect calcium channels.[1]

See also[edit]

References[edit]

  1. ^ King GF, Fletcher JI, Tedford HW (2001). "Functional significance of the beta hairpin in the insecticidal neurotoxin omega-atracotoxin-Hv1a". J. Biol. Chem. 276 (28): 26568–26576. doi:10.1074/jbc.M102199200. PMID 11313356.
This article incorporates text from the public domain Pfam and InterPro: IPR009415

One thought on “Cannabaceae

  1. Well, that’s interesting to know that Psilotum nudum are known as whisk ferns. Psilotum nudum is the commoner species of the two. While the P. flaccidum is a rare species and is found in the tropical islands. Both the species are usually epiphytic in habit and grow upon tree ferns. These species may also be terrestrial and grow in humus or in the crevices of the rocks.
    View the detailed Guide of Psilotum nudum: Detailed Study Of Psilotum Nudum (Whisk Fern), Classification, Anatomy, Reproduction

Leave a Reply