Names | |
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Preferred IUPAC name
(Z)-N1-[(2H-1,3-Benzodioxol-5-yl)methyl]-N′1-{2-[({5-[(dimethylamino)methyl]furan-2-yl}methyl)sulfanyl]ethyl}-2-nitroethene-1,1-diamine | |
Identifiers | |
3D model (JSmol)
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ChEMBL | |
ChemSpider | |
ECHA InfoCard | 100.076.612 |
EC Number |
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KEGG | |
MeSH | C073716 |
PubChem CID
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UNII | |
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Properties | |
C20H26N4O5S | |
Molar mass | 434.51 g·mol−1 |
Pharmacology | |
A02BA05 (WHO) | |
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
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Niperotidine is a histamine antagonist selective for the H2 subtype. It was studied as a treatment for excessive gastric acidity,[1] but withdrawn after human trials showed liver damage.[2]
References[edit]
- ^ Palasciano, G; Maggi, V; Portincasa, P (1990). "The effect of the H2-antagonist niperotidine on intragastric acidity in healthy subjects undergoing 24-hour pH-monitoring". The Italian Journal of Gastroenterology. 22 (5): 291–4. PMID 1983712.
- ^ Gasbarrini, G; Gentiloni, N; Febbraro, S; Gasbarrini, A; Di Campli, C; Cesana, M; Miglio, F; Miglioli, M; Ghinelli, F; d'Ambrosi, A; Amoroso, P; Pacini, F; Salvadori, G (1997). "Acute liver injury related to the use of niperotidine". Journal of Hepatology. 27 (3): 583–6. doi:10.1016/s0168-8278(97)80365-0. PMID 9314138.
Well, that’s interesting to know that Psilotum nudum are known as whisk ferns. Psilotum nudum is the commoner species of the two. While the P. flaccidum is a rare species and is found in the tropical islands. Both the species are usually epiphytic in habit and grow upon tree ferns. These species may also be terrestrial and grow in humus or in the crevices of the rocks.
View the detailed Guide of Psilotum nudum: Detailed Study Of Psilotum Nudum (Whisk Fern), Classification, Anatomy, Reproduction