Cannabaceae

Mizolastine
Clinical data
AHFS/Drugs.comInternational Drug Names
Routes of
administration
By mouth (tablets)
ATC code
Legal status
Legal status
  • UK: POM (Prescription only)
Identifiers
  • 2-[{1-[1-(4-Fluorobenzyl)-1H-benzimidazol-2-yl]piperidin-4-yl}(methyl)amino]pyrimidin-4(1H)-one
CAS Number
PubChem CID
ChemSpider
UNII
KEGG
ChEMBL
CompTox Dashboard (EPA)
ECHA InfoCard100.149.406 Edit this at Wikidata
Chemical and physical data
FormulaC24H25FN6O
Molar mass432.503 g·mol−1
3D model (JSmol)
  • CN(C1CCN(CC1)C2=NC3=CC=CC=C3N2CC4=CC=C(C=C4)F)C5=NC=CC(=O)N5
  • InChI=1S/C24H25FN6O/c1-29(23-26-13-10-22(32)28-23)19-11-14-30(15-12-19)24-27-20-4-2-3-5-21(20)31(24)16-17-6-8-18(25)9-7-17/h2-10,13,19H,11-12,14-16H2,1H3,(H,26,28,32) ☒N
  • Key:PVLJETXTTWAYEW-UHFFFAOYSA-N ☒N
 ☒NcheckY (what is this?)  (verify)

Mizolastine (Mizollen) is a once-daily, non-sedating antihistamine. It blocks H1 receptors and is commonly fast-acting.[1] It does not prevent the actual release of histamine from mast cells, it only prevents histamine from binding to receptors. Side effects can include dry mouth and throat.[2]

References

[edit]
  1. ^ Simons FE (March 1999). "Mizolastine: antihistaminic activity from preclinical data to clinical evaluation". Clinical and Experimental Allergy. 29 (Suppl 1): 3–8. doi:10.1046/j.1365-2222.1999.00002.x. PMID 10209699. S2CID 616333.
  2. ^ "MIZOLASTINE: British National Formulary". Retrieved 2010-02-01.


One thought on “Cannabaceae

  1. Well, that’s interesting to know that Psilotum nudum are known as whisk ferns. Psilotum nudum is the commoner species of the two. While the P. flaccidum is a rare species and is found in the tropical islands. Both the species are usually epiphytic in habit and grow upon tree ferns. These species may also be terrestrial and grow in humus or in the crevices of the rocks.
    View the detailed Guide of Psilotum nudum: Detailed Study Of Psilotum Nudum (Whisk Fern), Classification, Anatomy, Reproduction

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