Cannabaceae

Misonidazole
Names
IUPAC name
(RS)-1-Methoxy-3-(2-nitroimidazol-1-yl)propan-2-ol
Identifiers
3D model (JSmol)
ChEMBL
ChemSpider
ECHA InfoCard 100.033.559 Edit this at Wikidata
EC Number
  • 236-931-6
KEGG
MeSH D008920
UNII
  • InChI=1S/C7H11N3O4/c1-14-5-6(11)4-9-3-2-8-7(9)10(12)13/h2-3,6,11H,4-5H2,1H3 ☒N
    Key: OBBCSXFCDPPXOL-UHFFFAOYSA-N ☒N
  • InChI=1/C7H11N3O4/c1-14-5-6(11)4-9-3-2-8-7(9)10(12)13/h2-3,6,11H,4-5H2,1H3
    Key: OBBCSXFCDPPXOL-UHFFFAOYAQ
  • COCC(CN1C=CN=C1[N+](=O)[O-])O
Properties
C7H11N3O4
Molar mass 201.182 g·mol−1
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
☒N verify (what is checkY☒N ?)

Misonidazole is a radiosensitizer that was investigated in clinical trials. It was used in these trials for radiation therapy to cause normally resistant hypoxic tumor cells to become sensitive to the treatment.[1][2]

See also

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References

[edit]
  1. ^ Meißner, Rebecca; Feketeová, Linda; Illenberger, Eugen; Denifl, Stephan (2019). "Reactions in the Radiosensitizer Misonidazole Induced by Low-Energy (0–10 eV) Electrons". International Journal of Molecular Sciences. 20 (14): 3496. doi:10.3390/ijms20143496. PMC 6678818. PMID 31315268.
  2. ^ Overgaard, Jens (2011). "Hypoxic modification of radiotherapy in squamous cell carcinoma of the head and neck – A systematic review and meta-analysis". Radiotherapy and Oncology. 100 (1): 22–32. doi:10.1016/j.radonc.2011.03.004. PMID 21511351.


One thought on “Cannabaceae

  1. Well, that’s interesting to know that Psilotum nudum are known as whisk ferns. Psilotum nudum is the commoner species of the two. While the P. flaccidum is a rare species and is found in the tropical islands. Both the species are usually epiphytic in habit and grow upon tree ferns. These species may also be terrestrial and grow in humus or in the crevices of the rocks.
    View the detailed Guide of Psilotum nudum: Detailed Study Of Psilotum Nudum (Whisk Fern), Classification, Anatomy, Reproduction

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