Cannabaceae

MADAM-6
Names
Preferred IUPAC name
N-Methyl-1-(6-methyl-2H-1,3-benzodioxol-5-yl)propan-2-amine
Other names
6-Methyl-MDMA
Identifiers
3D model (JSmol)
ChemSpider
UNII
  • InChI=1S/C12H17NO2/c1-8-4-11-12(15-7-14-11)6-10(8)5-9(2)13-3/h4,6,9,13H,5,7H2,1-3H3
    Key: CRQPDNIUPWXPNK-UHFFFAOYSA-N
  • C1(=CC2=C(C=C1CC(C)NC)OCO2)C
Properties
C12H17NO2
Molar mass 207.273 g·mol−1
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).

MADAM-6, or 2, N-dimethyl-4,5-methylenedioxyamphetamine, is a lesser-known recreational drug of the methamphetamine class, similar in structure to MDMA (ecstasy).[1] MADAM-6 was first synthesized by Alexander Shulgin.[2] In Shulgin's book PiHKAL, the minimum dosage is listed as greater than 280 mg, and the duration is unknown.[2] MADAM-6 produces few to no effects and Shulgin describes it as "not active".[2] Very little data exists about the pharmacological properties, metabolism, and toxicity of MADAM-6.

MADAM-6 has been studied for its potential antiparkinsonian effects.[3] However, no clinical trials suggest the drug is effective against Parkinson's disease.

See also[edit]

References[edit]

  1. ^ Patt, M; Gündisch, D; Wüllner, U; Blocher, A; Kovar, K. -A; Machulla, H. -J (1999). "N-[11C]methyl-3,4-methylenedioxyamphetamine (Ecstasy) and 2-methyl-N-[11C]methyl-4,5-methylenedioxyamphetamine: Synthesis and biodistribution studies". Journal of Radioanalytical and Nuclear Chemistry. 240 (2): 535. doi:10.1007/BF02349410. S2CID 96272983.
  2. ^ a b c MADAM-6 entry in PiHKAL
  3. ^ US patent US2015025063, Caron; Gainetdinov & Sotnikova, "Antiparkinsonian Action Of Phenylisopropylamines", published 2014-09-30, issued 2015-01-22 


One thought on “Cannabaceae

  1. Well, that’s interesting to know that Psilotum nudum are known as whisk ferns. Psilotum nudum is the commoner species of the two. While the P. flaccidum is a rare species and is found in the tropical islands. Both the species are usually epiphytic in habit and grow upon tree ferns. These species may also be terrestrial and grow in humus or in the crevices of the rocks.
    View the detailed Guide of Psilotum nudum: Detailed Study Of Psilotum Nudum (Whisk Fern), Classification, Anatomy, Reproduction

Leave a Reply