THC Science

MYO18A
Identifiers
Aliases	MYO18A, MYSPDZ, SPR210, myosin XVIIIA, MAJN, SP-R210
External IDs	OMIM: 610067; MGI: 2667185; HomoloGene: 7977; GeneCards: MYO18A; OMA:MYO18A - orthologs
Gene location (Human)
Chr.	Chromosome 17 (human)
End	29,180,398 bp
Gene location (Mouse)
Chr.	Chromosome 11 (mouse)
End	77,865,980 bp
RNA expression pattern
	Top expressed in
	Top expressed in
	More reference expression data
	n/a
Gene ontology
Molecular function
Cellular component
Biological process
	Sources:Amigo / QuickGO
Orthologs
	399687
	360013
	ENSG00000196535
	ENSMUSG00000000631
	Q92614
	Q9JMH9
NM_001346765; NM_001346766; NM_001346767; NM_001346768; NM_078471;
	NM_203318
	NM_001291212; NM_001291213; NM_001291214; NM_001291215; NM_011586
NP_001333694; NP_001333695; NP_001333696; NP_001333697; NP_510880;
	NP_976063
	NP_001278141; NP_001278142; NP_001278143; NP_001278144; NP_035716
	Wikidata
View/Edit Human	View/Edit Mouse

Myosin-XVIIIa is a protein that in humans is encoded by the MYO18A gene.^[5]^[6]

References[edit]

^ ^a ^b ^c GRCh38: Ensembl release 89: ENSG00000196535 – Ensembl, May 2017
^ ^a ^b ^c GRCm38: Ensembl release 89: ENSMUSG00000000631 – Ensembl, May 2017
^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ Mori K, Furusawa T, Okubo T, Inoue T, Ikawa S, Yanai N, Mori KJ, Obinata M (May 2003). "Genome structure and differential expression of two isoforms of a novel PDZ-containing myosin (MysPDZ) (Myo18A)". J Biochem. 133 (4): 405–13. doi:10.1093/jb/mvg053. PMID 12761286.
^ "Entrez Gene: MYO18A myosin XVIIIA".

Further reading[edit]

Chroneos ZC, Abdolrasulnia R, Whitsett JA, et al. (1996). "Purification of a cell-surface receptor for surfactant protein A." J. Biol. Chem. 271 (27): 16375–83. doi:10.1074/jbc.271.27.16375. PMID 8663107.
Nagase T, Seki N, Ishikawa K, et al. (1997). "Prediction of the coding sequences of unidentified human genes. VI. The coding sequences of 80 new genes (KIAA0201-KIAA0280) deduced by analysis of cDNA clones from cell line KG-1 and brain". DNA Res. 3 (5): 321–9, 341–54. doi:10.1093/dnares/3.5.321. PMID 9039502.
Chang NS, Mattison J, Cao H, et al. (1999). "Cloning and characterization of a novel transforming growth factor-beta1-induced TIAF1 protein that inhibits tumor necrosis factor cytotoxicity". Biochem. Biophys. Res. Commun. 253 (3): 743–9. doi:10.1006/bbrc.1998.9846. PMID 9918798.
Ji H, Zhai Q, Zhu J, et al. (2000). "A novel protein MAJN binds to Jak3 and inhibits apoptosis induced by IL-2 deprival". Biochem. Biophys. Res. Commun. 270 (1): 267–71. doi:10.1006/bbrc.2000.2413. PMID 10733938.
Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. Bibcode:2002PNAS...9916899M. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs". Nat. Genet. 36 (1): 40–5. doi:10.1038/ng1285. PMID 14702039.
Beausoleil SA, Jedrychowski M, Schwartz D, et al. (2004). "Large-scale characterization of HeLa cell nuclear phosphoproteins". Proc. Natl. Acad. Sci. U.S.A. 101 (33): 12130–5. Bibcode:2004PNAS..10112130B. doi:10.1073/pnas.0404720101. PMC 514446. PMID 15302935.
Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC 528928. PMID 15489334.
Homma K, Kikuno RF, Nagase T, et al. (2004). "Alternative splice variants encoding unstable protein domains exist in the human brain". J. Mol. Biol. 343 (5): 1207–20. doi:10.1016/j.jmb.2004.09.028. PMID 15491607.
Isogawa Y, Kon T, Inoue T, et al. (2005). "The N-terminal domain of MYO18A has an ATP-insensitive actin-binding site". Biochemistry. 44 (16): 6190–6. doi:10.1021/bi0475931. PMID 15835906.
Kim JE, Tannenbaum SR, White FM (2005). "Global phosphoproteome of HT-29 human colon adenocarcinoma cells". J. Proteome Res. 4 (4): 1339–46. doi:10.1021/pr050048h. PMID 16083285.
Yang CH, Szeliga J, Jordan J, et al. (2005). "Identification of the surfactant protein A receptor 210 as the unconventional myosin 18A". J. Biol. Chem. 280 (41): 34447–57. doi:10.1074/jbc.M505229200. PMC 1762002. PMID 16087679.
Lim J, Hao T, Shaw C, et al. (2006). "A protein-protein interaction network for human inherited ataxias and disorders of Purkinje cell degeneration". Cell. 125 (4): 801–14. doi:10.1016/j.cell.2006.03.032. PMID 16713569. S2CID 13709685.
Olsen JV, Blagoev B, Gnad F, et al. (2006). "Global, in vivo, and site-specific phosphorylation dynamics in signaling networks". Cell. 127 (3): 635–48. doi:10.1016/j.cell.2006.09.026. PMID 17081983. S2CID 7827573.

[refGRCh38Ensembl-1] GRCh38: Ensembl release 89: ENSG00000196535 – Ensembl, May 2017

[refGRCm38Ensembl-2] GRCm38: Ensembl release 89: ENSMUSG00000000631 – Ensembl, May 2017

[3] "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[4] "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[pmid12761286-5] Mori K, Furusawa T, Okubo T, Inoue T, Ikawa S, Yanai N, Mori KJ, Obinata M (May 2003). "Genome structure and differential expression of two isoforms of a novel PDZ-containing myosin (MysPDZ) (Myo18A)". J Biochem. 133 (4): 405–13. doi:10.1093/jb/mvg053. PMID 12761286.

[entrez-6] "Entrez Gene: MYO18A myosin XVIIIA".

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