Cannabaceae

MTF1
Identifiers
AliasesMTF1, MTF-1, ZRF, metal-regulatory transcription factor 1, metal regulatory transcription factor 1
External IDsOMIM: 600172; MGI: 101786; HomoloGene: 4347; GeneCards: MTF1; OMA:MTF1 - orthologs
Orthologs
SpeciesHumanMouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_005955

NM_008636

RefSeq (protein)

NP_005946

NP_032662

Location (UCSC)Chr 1: 37.81 – 37.86 MbChr 4: 124.7 – 124.74 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

Metal regulatory transcription factor 1 is a protein that in humans is encoded by the MTF1 gene.[5][6]

Function[edit]

This gene encodes a transcription factor that induces expression of metallothioneins and other genes involved in metal homeostasis in response to heavy metals such as cadmium, zinc, copper, and silver. The protein is a nucleocytoplasmic shuttling protein that accumulates in the nucleus upon heavy metal exposure and binds to promoters containing a metal-responsive element (MRE).[6]

References[edit]

  1. ^ a b c GRCh38: Ensembl release 89: ENSG00000188786Ensembl, May 2017
  2. ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000028890Ensembl, May 2017
  3. ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. ^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. ^ Brugnera E, Georgiev O, Radtke F, Heuchel R, Baker E, Sutherland GR, Schaffner W (Aug 1994). "Cloning, chromosomal mapping and characterization of the human metal-regulatory transcription factor MTF-1". Nucleic Acids Research. 22 (15): 3167–73. doi:10.1093/nar/22.15.3167. PMC 310292. PMID 8065932.
  6. ^ a b "Entrez Gene: MTF1 metal-regulatory transcription factor 1".

Further reading[edit]

External links[edit]

This article incorporates text from the United States National Library of Medicine, which is in the public domain.

One thought on “Cannabaceae

  1. Well, that’s interesting to know that Psilotum nudum are known as whisk ferns. Psilotum nudum is the commoner species of the two. While the P. flaccidum is a rare species and is found in the tropical islands. Both the species are usually epiphytic in habit and grow upon tree ferns. These species may also be terrestrial and grow in humus or in the crevices of the rocks.
    View the detailed Guide of Psilotum nudum: Detailed Study Of Psilotum Nudum (Whisk Fern), Classification, Anatomy, Reproduction

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