Monoclonal antibody | |
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Type | Whole antibody |
Source | Chimeric (primate/human) |
Target | CD4 |
Clinical data | |
Routes of administration | intravenous |
ATC code |
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Identifiers | |
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Keliximab is a monoclonal antibody for the treatment of severe chronic asthma. It suppresses the immune reaction by binding to white blood cells via the protein CD4.[1] The drug is a chimeric antibody from Macaca irus and Homo sapiens.[2]
References[edit]
- ^ Kon OM, Sihra BS, Compton CH, Leonard TB, Kay AB, Barnes NC (October 1998). "Randomised, dose-ranging, placebo-controlled study of chimeric antibody to CD4 (keliximab) in chronic severe asthma". Lancet. 352 (9134): 1109–13. doi:10.1016/S0140-6736(97)12261-9. PMID 9798587. S2CID 29868851.
- ^ "Proposed INN List" (PDF). WHO Drug Information. 10 (4). 1996. Archived from the original (PDF) on November 13, 2008.
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