The Ivanov reaction is the chemical reaction of the dianions (endiolates) of aryl acetic acids (Ivanov reagents) with electrophiles, primarily carbonyl compounds or isocyanates.[1][2][3][4] The reaction was named after the Bulgarian organic chemist, Academician Dimitar Ivanov, who discovered it.
Ivanov reagents (dianions of aryl acetic acids) react with many electrophiles, including aldehydes, ketones, isocyanates, and alkyl halides.[5] The product does not usually spontaneously decarboxylate, but it is possible with some reagents.
The Ivanov reaction is known to proceed through the Zimmerman-Traxler model transition state[6]. Toulec et al. have investigated the reaction rates and kinetics.[7]
See also[edit]
References[edit]
- ^ Ivanov, D.; Spassoff, A. Bull. Soc. Chim. France 1931, 49, 19 & 375.
- ^ Ivanov, D. et al. Bull. Soc. Chim. France 1932, 51, 1321 & 1325 & 1331.
- ^ Blagoev, B.; Ivanov, D. Synthesis 1970, 615–627. (Review)
- ^ Ivanov, D. Synthesis 1975, 83–98. (Review)
- ^ Hauser, C. R.; Dunnavant, W. R. (1960). "α,β-Diphenylpropionic acid". Organic Syntheses. 40: 38. doi:10.15227/orgsyn.040.0038.
- ^ Zimmerman, H. E.; Traxler, M. D. (1957). "The Stereochemistry of the Ivanov and Reformatsky Reactions". Journal of the American Chemical Society. 79 (8): 1920–1923. doi:10.1021/ja01565a041.
- ^ Toullec, J.; Mladenova, M.; Gaudemar-Bardone, F.; Blagoev, B. J. Org. Chem. 1985, 50, 2563.
Well, that’s interesting to know that Psilotum nudum are known as whisk ferns. Psilotum nudum is the commoner species of the two. While the P. flaccidum is a rare species and is found in the tropical islands. Both the species are usually epiphytic in habit and grow upon tree ferns. These species may also be terrestrial and grow in humus or in the crevices of the rocks.
View the detailed Guide of Psilotum nudum: Detailed Study Of Psilotum Nudum (Whisk Fern), Classification, Anatomy, Reproduction