Cannabaceae

thcscience_admin
Ipsapirone
Clinical data
Routes of
administration		Oral
ATC code
  • none
Legal status
Legal status
  • In general: uncontrolled
Pharmacokinetic data
Elimination half-life1.3–2.7 hours[medical citation needed]
Identifiers
  • 9,9-dioxo-8-[4-(4-pyrimidin-2-ylpiperazin-1-yl)butyl]-
    9λ6-thia-8-azabicyclo[4.3.0]nona-1,3,5-trien-7-one
CAS Number
PubChem CID
IUPHAR/BPS
ChemSpider
UNII
ChEMBL
CompTox Dashboard (EPA)
Chemical and physical data
FormulaC19H23N5O3S
Molar mass401.49 g·mol−1
3D model (JSmol)
  • O=C2c1ccccc1S(=O)(=O)N2CCCCN4CCN(c3ncccn3)CC4
  • InChI=1S/C19H23N5O3S/c25-18-16-6-1-2-7-17(16)28(26,27)24(18)11-4-3-10-22-12-14-23(15-13-22)19-20-8-5-9-21-19/h1-2,5-9H,3-4,10-15H2 checkY
  • Key:TZJUVVIWVWFLCD-UHFFFAOYSA-N checkY
  (verify)

Ipsapirone is a selective 5-HT1A receptor partial agonist of the piperazine and azapirone chemical classes.[1] It has antidepressant and anxiolytic effects.[1] Ipsapirone was studied in several placebo-controlled trials for depression and continues to be used in research.[2]

See also[edit]

References[edit]

  1. ^ a b Fanelli RJ, Schuurman T, Glaser T, Traber J (1990). "Ipsapirone: a novel anxiolytic and selective 5-HT1A receptor ligand". Progress in Clinical and Biological Research. 361: 461–467. PMID 1981264.
  2. ^ Chessick CA, Allen MH, Thase M, Batista Miralha da Cunha AB, Kapczinski FF, de Lima MS, dos Santos Souza JJ (July 2006). "Azapirones for generalized anxiety disorder". The Cochrane Database of Systematic Reviews. 2006 (3): CD006115. doi:10.1002/14651858.CD006115. PMC 8915394. PMID 16856115.
source: https://en.wikipedia.org/wiki/Ipsapirone

One thought on “Cannabaceae”

  1. Well, that’s interesting to know that Psilotum nudum are known as whisk ferns. Psilotum nudum is the commoner species of the two. While the P. flaccidum is a rare species and is found in the tropical islands. Both the species are usually epiphytic in habit and grow upon tree ferns. These species may also be terrestrial and grow in humus or in the crevices of the rocks.
    View the detailed Guide of Psilotum nudum: Detailed Study Of Psilotum Nudum (Whisk Fern), Classification, Anatomy, Reproduction

Leave a Reply