Cannabaceae

Indenolol
Names
IUPAC name
1-(1H-Inden-4-yloxy)-3-(propan-2-ylamino)propan-2-ol
Identifiers
3D model (JSmol)
ChEMBL
ChemSpider
DrugBank
EC Number
  • 262-323-5
KEGG
UNII
  • InChI=1S/C15H21NO2/c1-11(2)16-9-13(17)10-18-15-8-4-6-12-5-3-7-14(12)15/h3-4,6-8,11,13,16-17H,5,9-10H2,1-2H3
    Key: MPGBPFMOOXKQRX-UHFFFAOYSA-N
  • InChI=1/C15H21NO2/c1-11(2)16-9-13(17)10-18-15-8-4-6-12-5-3-7-14(12)15/h3-4,6-8,11,13,16-17H,5,9-10H2,1-2H3
    Key: MPGBPFMOOXKQRX-UHFFFAOYAY
  • CC(C)NCC(COC1=CC=CC2=C1C=CC2)O
Properties
C15H21NO2
Molar mass 247.338 g·mol−1
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).

Indenolol is a beta-adrenergic blocker[1] for the treatment of hypertension (high blood pressure). It was investigated in the 1980s,[2] but is not known to be marketed as of 2021.[3] It is a derivative of a phenolic 4-indenol.

References[edit]

  1. ^ Ali, I; Gaitonde, VD; Aboul-Enein, HY; Hussain, A (2009). "Chiral separation of beta-adrenergic blockers on CelluCoat column by HPLC". Talanta. 78 (2): 458–63. doi:10.1016/j.talanta.2008.11.043. PMID 19203609.
  2. ^ Trimarco, Bruno; Cuocolo, Alberto; Groothold, Gisela; Ricciardelli, Bruno; De Luca, Nicola; Volpe, Massimo; Veniero, Anna Maria; Condorelli, Mario (1985). "Indenolol: A New Antihypertensive Agent: Efficacy, Toxicity, and Hemodynamic Effects in a Crossover Double-Blind Study with Metoprolol". The Journal of Clinical Pharmacology. 25 (5): 328–336. doi:10.1002/j.1552-4604.1985.tb02850.x. PMID 4031109. S2CID 22844379.
  3. ^ DrugBank DB08952 . Accessed 2021-03-18.


One thought on “Cannabaceae

  1. Well, that’s interesting to know that Psilotum nudum are known as whisk ferns. Psilotum nudum is the commoner species of the two. While the P. flaccidum is a rare species and is found in the tropical islands. Both the species are usually epiphytic in habit and grow upon tree ferns. These species may also be terrestrial and grow in humus or in the crevices of the rocks.
    View the detailed Guide of Psilotum nudum: Detailed Study Of Psilotum Nudum (Whisk Fern), Classification, Anatomy, Reproduction

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