Cannabaceae

thcscience_admin
1-Indanone
Names
Preferred IUPAC name
2,3-Dihydro-1H-inden-1-one
Other names
α-Hydroindone
Identifiers
3D model (JSmol)
3DMet
507957
ChEBI
ChemSpider
ECHA InfoCard 100.001.337 Edit this at Wikidata
EC Number
  • 201-470-1
142414
KEGG
UNII
  • InChI=1S/C9H8O/c10-9-6-5-7-3-1-2-4-8(7)9/h1-4H,5-6H2
    Key: QNXSIUBBGPHDDE-UHFFFAOYSA-N
  • C1CC(=O)C2=CC=CC=C21
Properties
C9H8O
Molar mass 132.162 g·mol−1
Appearance Colorless solid
Melting point 38–42 °C (100–108 °F; 311–315 K)
Boiling point 243–245 °C (469–473 °F; 516–518 K)
Hazards
GHS labelling:
GHS07: Exclamation mark
Warning
H302
P261, P264, P270, P271, P280, P301+P312, P302+P352, P304+P340, P305+P351+P338, P312, P321, P330, P332+P313, P337+P313, P362, P403+P233, P405, P501
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).

1-Indanone is the organic compound with the formula C6H4(CH2)2CO. It is one of two isomeric benzocyclopentanones, the other being 2-indanone. It is a colorless solid. 1-Indanone is a substrate for the enzyme indanol dehydrogenase.

Preparation

[edit]

It is prepared by oxidation of indane or indene.[1] It can also be prepared by cyclization of phenylpropionic acid.

List of Drugs

[edit]
  1. 2-Aminoindan synthesis (MDAI methodology using beta-keto-oxime formation with isoamylnitrite followed by reduction)
  2. Drinidene
  3. LNK-121[2]
  4. Pirandamine
  5. Pyrophendane
  6. SKF Derivatives[3][4]
  7. Indane analog of nisoxetine or Prozac.[5]

References

[edit]
  1. ^ R. A. Pacaud, C. F. H. Allen (1938). "α-Hydroindone". Org. Synth. 18: 47. doi:10.15227/orgsyn.018.0047.
  2. ^ Peter T. Lansbury, Jr. Craig J. Justman, US20100292292 (2010 to Link Medicine Corp)
  3. ^ Ganellin, C. R.; Loynes, J. M.; Ridley, H. F.; Spickett, R. G. W. (1967). "Compounds Affecting the Central Nervous System. IV. Substituted 2-Benzyl-3-dialkylaminoalkylindenes and Related Compounds". Journal of Medicinal Chemistry. 10 (5): 826–833. doi:10.1021/jm00317a016.
  4. ^ Jack David, Spickett Robert Geoffr William & Ganellin Charon Robin, U.S. patent 3,159,634 (1964 to Smith Kline and French Laboratories Ltd).
  5. ^ Jules Freedman, U.S. patent 5,149,714 (1992 to Aventis Inc)
source: https://en.wikipedia.org/wiki/Indanone

One thought on “Cannabaceae”

  1. Well, that’s interesting to know that Psilotum nudum are known as whisk ferns. Psilotum nudum is the commoner species of the two. While the P. flaccidum is a rare species and is found in the tropical islands. Both the species are usually epiphytic in habit and grow upon tree ferns. These species may also be terrestrial and grow in humus or in the crevices of the rocks.
    View the detailed Guide of Psilotum nudum: Detailed Study Of Psilotum Nudum (Whisk Fern), Classification, Anatomy, Reproduction

Leave a Reply