Cannabaceae

Hydroxyethylrutosides (oxerutins, O-beta-hydroxyethyl-rutosides, HR, or HER) are hydroxyethyl derivatives of rutosides. Examples include:

Oxerutins are semisynthetic derivatives of plant constituents. Although they are closely related to the natural flavonoid rutin, hydroxyethylrutosides are not found in food. The only way to take them is in a supplement.[1]

Health benefits[edit]

Relvène (1967 French version), Venoruton (1962 Swiss version), and Paroven are mixtures of hydroxyethyl rutinosides. Hydroxyethylrutosides are used in the treatment of chronic venous insufficiency[2] and hypertensive microangiopathy.[3] Oxerutins work by reducing leakage from the small blood vessels (capillaries).[4]

Hydroxyethylrutosides have been used as an alternative to horse chestnut preparations (venostasin) containing aescin. Typical doses are in the order of 1,000 mg/day.[5]

Effects of hydroxyethylrutosides against adriamycin-induced toxicity have been investigated in rats.[6]

References[edit]

  1. ^ Oxerutins on healthlibrary.epnet.com
  2. ^ Frick, RW (2000). "Three treatments for chronic venous insufficiency: Escin, hydroxyethylrutoside, and Daflon". Angiology. 51 (3): 197–205. doi:10.1177/000331970005100303. PMID 10744007. S2CID 19421726.
  3. ^ Incandela, L; Belcaro, G; Renton, S; Desanctis, MT; Cesarone, MR; Bavera, P; Ippolito, E; Bucci, M; et al. (2002). "HR (Paroven, Venoruton; 0-(beta-hydroxyethyl)-rutosides) in venous hypertensive microangiopathy: A prospective, placebo-controlled, randomized trial". Journal of Cardiovascular Pharmacology and Therapeutics. 7 (Suppl 1): S7–S10. doi:10.1177/107424840200700103. PMID 12011966. S2CID 9720685.
  4. ^ Paroven on netdoctor.co.uk
  5. ^ The handbook of clinically tested herbal remedies, Volume 2 by Marilyn Barrett
  6. ^ Gulati, OP; Nordmann, H; Aellig, A; Maignan, MF; McGinness, J (1985). "Protective effects of O-(beta-hydroxyethyl)-rutosides (HR) against adriamycin-induced toxicity in rats". Archives Internationales de Pharmacodynamie et de Thérapie. 273 (2): 323–34. PMID 4004421.

One thought on “Cannabaceae

  1. Well, that’s interesting to know that Psilotum nudum are known as whisk ferns. Psilotum nudum is the commoner species of the two. While the P. flaccidum is a rare species and is found in the tropical islands. Both the species are usually epiphytic in habit and grow upon tree ferns. These species may also be terrestrial and grow in humus or in the crevices of the rocks.
    View the detailed Guide of Psilotum nudum: Detailed Study Of Psilotum Nudum (Whisk Fern), Classification, Anatomy, Reproduction

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