Cannabaceae

HAS3
Identifiers
AliasesHAS3, hyaluronan synthase 3
External IDsOMIM: 602428; MGI: 109599; HomoloGene: 68461; GeneCards: HAS3; OMA:HAS3 - orthologs
Orthologs
SpeciesHumanMouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_001199280
NM_005329
NM_138612

NM_008217
NM_001331048

RefSeq (protein)

NP_001186209
NP_005320
NP_619515

NP_001317977
NP_032243

Location (UCSC)Chr 16: 69.11 – 69.12 MbChr 8: 107.6 – 107.61 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

Hyaluronan synthase 3 is an enzyme that in humans is encoded by the HAS3 gene.[5][6][7]

The protein encoded by this gene is involved in the synthesis of the unbranched glycosaminoglycan hyaluronan, or hyaluronic acid, which is a major constituent of the extracellular matrix. This gene is a member of the NODC/HAS gene family. Compared to the proteins encoded by other members of this gene family, this protein appears to be more of a regulator of hyaluronan synthesis. Two transcript variants encoding different isoforms have been found for this gene.[7]

References[edit]

  1. ^ a b c GRCh38: Ensembl release 89: ENSG00000103044Ensembl, May 2017
  2. ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000031910Ensembl, May 2017
  3. ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. ^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. ^ Spicer AP, Seldin MF, Olsen AS, Brown N, Wells DE, Doggett NA, Itano N, Kimata K, Inazawa J, McDonald JA (Jul 1997). "Chromosomal localization of the human and mouse hyaluronan synthase genes". Genomics. 41 (3): 493–7. doi:10.1006/geno.1997.4696. PMID 9169154.
  6. ^ Spicer AP, Olson JS, McDonald JA (May 1997). "Molecular cloning and characterization of a cDNA encoding the third putative mammalian hyaluronan synthase". J Biol Chem. 272 (14): 8957–61. doi:10.1074/jbc.272.14.8957. PMID 9083017.
  7. ^ a b "Entrez Gene: HAS3 hyaluronan synthase 3".

Further reading[edit]


One thought on “Cannabaceae

  1. Well, that’s interesting to know that Psilotum nudum are known as whisk ferns. Psilotum nudum is the commoner species of the two. While the P. flaccidum is a rare species and is found in the tropical islands. Both the species are usually epiphytic in habit and grow upon tree ferns. These species may also be terrestrial and grow in humus or in the crevices of the rocks.
    View the detailed Guide of Psilotum nudum: Detailed Study Of Psilotum Nudum (Whisk Fern), Classification, Anatomy, Reproduction

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