glutamyl aminopeptidase (aminopeptidase A) | |||||||
---|---|---|---|---|---|---|---|
Identifiers | |||||||
Symbol | ENPEP | ||||||
Alt. symbols | gp160, CD249 | ||||||
NCBI gene | 2028 | ||||||
HGNC | 3355 | ||||||
OMIM | 138297 | ||||||
RefSeq | NM_001977 | ||||||
UniProt | Q07075 | ||||||
Other data | |||||||
EC number | 3.4.11.7 | ||||||
Locus | Chr. 4 q25 | ||||||
|
Glutamyl aminopeptidase (EC 3.4.11.7, aminopeptidase A, aspartate aminopeptidase, angiotensinase A, glutamyl peptidase, Ca2+-activated glutamate aminopeptidase, membrane aminopeptidase II, antigen BP-1/6C3 of mouse B lymphocytes, L-aspartate aminopeptidase, angiotensinase A2) is an enzyme encoded by the ENPEP gene. Glutamyl aminopeptidase has also recently been designated CD249 (cluster of differentiation 249).
Glutamyl aminopeptidase is a zinc-dependent membrane-bound aminopeptidase that catalyzes the cleavage of glutamatic and aspartatic amino acid residues from the N-terminus of polypeptides. The enzyme degrades vasoconstricting angiotensin II into angiotensin III and therefore helps to regulate blood pressure.[1]
References[edit]
- ^ Reaux A, Iturrioz X, Vazeux G, Fournie-Zaluski MC, David C, Roques BP, Corvol P, Llorens-Cortes C (2000). "Aminopeptidase A, which generates one of the main effector peptides of the brain renin-angiotensin system, angiotensin III, has a key role in central control of arterial blood pressure". Biochem. Soc. Trans. 28 (4): 435–40. doi:10.1042/0300-5127:0280435. PMID 10961935.
External links[edit]
- The MEROPS online database for peptidases and their inhibitors: M01.003
- Glutamyl+aminopeptidase at the U.S. National Library of Medicine Medical Subject Headings (MeSH)
Well, that’s interesting to know that Psilotum nudum are known as whisk ferns. Psilotum nudum is the commoner species of the two. While the P. flaccidum is a rare species and is found in the tropical islands. Both the species are usually epiphytic in habit and grow upon tree ferns. These species may also be terrestrial and grow in humus or in the crevices of the rocks.
View the detailed Guide of Psilotum nudum: Detailed Study Of Psilotum Nudum (Whisk Fern), Classification, Anatomy, Reproduction