Cannabaceae

MOGS
Identifiers
AliasesMOGS, CDG2B, CWH41, DER7, GCS1, mannosyl-oligosaccharide glucosidase
External IDsOMIM: 601336; MGI: 1929872; HomoloGene: 4593; GeneCards: MOGS; OMA:MOGS - orthologs
Orthologs
SpeciesHumanMouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_006302
NM_001146158

NM_020619

RefSeq (protein)

NP_001139630
NP_006293

NP_065644

Location (UCSC)n/aChr 6: 83.09 – 83.1 Mb
PubMed search[2][3]
Wikidata
View/Edit HumanView/Edit Mouse

Mannosyl-oligosaccharide glucosidase is an enzyme that in humans is encoded by the MOGS gene.[4][5][6]

Glucosidase I is the first enzyme in the N-linked oligosaccharide processing pathway. GCS1 cleaves the distal alpha-1,2-linked glucose residue from the Glc(3)-Man(9)-GlcNAc(2) oligosaccharide precursor. GCS1 is located in the lumen of the endoplasmic reticulum.[6]

GCS1 may also refer to "generative cell specific 1", also called HAP2 (hapless2), a gene of lower eukaryotes which is thought to be responsible for gametes fusion .[7] .

References

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  1. ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000030036Ensembl, May 2017
  2. ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  3. ^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. ^ Kalz-Fuller B, Bieberich E, Bause E (Sep 1995). "Sexualization and expression of glucosidase I from human hippocampus". Eur J Biochem. 231 (2): 344–51. doi:10.1111/j.1432-1033.1995.tb20706.x. PMID 7635146.
  5. ^ Kalz-Fuller B, Heidrich-Kaul C, Nothen M, Bause E, Schwanitz G (Sep 1996). "Localization of the human glucosidase I gene to chromosome 2p12-p13 by fluorescence in situ hybridization and PCR analysis of somatic cell hybrids". Genomics. 34 (3): 442–3. doi:10.1006/geno.1996.0313. PMID 8786151.
  6. ^ a b "Entrez Gene: GCS1 glucosidase I".
  7. ^ Goodman CD, McFadden GI (2008). "Gamete Fusion: Key Protein Identified". Current Biology. 18 (13): R571–R573. Bibcode:2008CBio...18.R571G. doi:10.1016/j.cub.2008.05.007. PMID 18606131. S2CID 14367758.

Further reading

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One thought on “Cannabaceae

  1. Well, that’s interesting to know that Psilotum nudum are known as whisk ferns. Psilotum nudum is the commoner species of the two. While the P. flaccidum is a rare species and is found in the tropical islands. Both the species are usually epiphytic in habit and grow upon tree ferns. These species may also be terrestrial and grow in humus or in the crevices of the rocks.
    View the detailed Guide of Psilotum nudum: Detailed Study Of Psilotum Nudum (Whisk Fern), Classification, Anatomy, Reproduction

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