Cannabaceae

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Fluotracen
Skeletal formula of fluotracen
Ball-and-stick model of the fluotracen molecule
Clinical data
Routes of
administration		Oral
ATC code
  • none
Legal status
Legal status
  • In general: uncontrolled
Identifiers
  • N,N-dimethyl-3-[10-methyl-2-(trifluoromethyl)-9,10-dihydroanthracen-9-yl]propan-1-amine
CAS Number
PubChem CID
ChemSpider
UNII
CompTox Dashboard (EPA)
Chemical and physical data
FormulaC21H24F3N
Molar mass347.425 g·mol−1
3D model (JSmol)
  • FC(F)(F)c1ccc3c(c1)C(c2ccccc2C3C)CCCN(C)C

Fluotracen (SKF-28,175) is a tricyclic drug which has both antidepressant and antipsychotic activity.[1][2][3] This profile of effects is similar to that of related agents like amoxapine, loxapine, and trimipramine which may also be used in the treatment of both depression and psychosis.[1] It was believed that such duality would be advantageous in the treatment of schizophrenia, as depression is often comorbid with the disorder and usual antipsychotics often worsen such symptoms.[1] In any case, however, fluotracen was never marketed.[3]

See also[edit]

References[edit]

  1. ^ a b c Annual Reports in Medicinal Chemistry: v. 14. Academic Press Inc.,U.S. 1979. ISBN 0-12-040514-8.
  2. ^ Fowler PJ, Zirkle CL, Macko E, et al. (1977). "Fluotracen: a tricyclic compound with the combined properties of antidepressants and antipsychotics in animals". Arzneimittel-Forschung. 27 (8): 1589–95. PMID 410422.
  3. ^ a b David J. Triggle (1996). Dictionary of Pharmacological Agents. Boca Raton: Chapman & Hall/CRC. ISBN 0-412-46630-9.
source: https://en.wikipedia.org/wiki/Fluotracen

One thought on “Cannabaceae”

  1. Well, that’s interesting to know that Psilotum nudum are known as whisk ferns. Psilotum nudum is the commoner species of the two. While the P. flaccidum is a rare species and is found in the tropical islands. Both the species are usually epiphytic in habit and grow upon tree ferns. These species may also be terrestrial and grow in humus or in the crevices of the rocks.
    View the detailed Guide of Psilotum nudum: Detailed Study Of Psilotum Nudum (Whisk Fern), Classification, Anatomy, Reproduction

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