Cannabaceae

FZD10
Identifiers
AliasesFZD10, CD350, FZ-10, Fz10, FzE7, hFz10, frizzled class receptor 10
External IDsOMIM: 606147; MGI: 2136761; HomoloGene: 21411; GeneCards: FZD10; OMA:FZD10 - orthologs
Orthologs
SpeciesHumanMouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_007197

NM_175284

RefSeq (protein)

NP_009128

NP_780493

Location (UCSC)Chr 12: 130.16 – 130.17 MbChr 5: 128.68 – 128.68 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

Frizzled-10 (Fz-10) is a protein that in humans is encoded by the FZD10 gene.[5][6] Fz-10 has also been designated as CD350 (cluster of differentiation 350).

Function[edit]

This gene is a member of the frizzled gene family. Members of this family encode 7-transmembrane domain proteins that are receptors for the Wingless type MMTV integration site family of signaling proteins. Most frizzled receptors are coupled to the beta-catenin canonical signaling pathway. Using array analysis, expression of this intronless gene is significantly up-regulated in two cases of primary colon cancer.[6]

References[edit]

  1. ^ a b c GRCh38: Ensembl release 89: ENSG00000111432Ensembl, May 2017
  2. ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000081683Ensembl, May 2017
  3. ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. ^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. ^ Koike J, Takagi A, Miwa T, Hirai M, Terada M, Katoh M (Aug 1999). "Molecular cloning of Frizzled-10, a novel member of the Frizzled gene family". Biochemical and Biophysical Research Communications. 262 (1): 39–43. doi:10.1006/bbrc.1999.1161. PMID 10448064.
  6. ^ a b "Entrez Gene: FZD10 frizzled homolog 10 (Drosophila)".

Further reading[edit]

External links[edit]

This article incorporates text from the United States National Library of Medicine, which is in the public domain.


One thought on “Cannabaceae

  1. Well, that’s interesting to know that Psilotum nudum are known as whisk ferns. Psilotum nudum is the commoner species of the two. While the P. flaccidum is a rare species and is found in the tropical islands. Both the species are usually epiphytic in habit and grow upon tree ferns. These species may also be terrestrial and grow in humus or in the crevices of the rocks.
    View the detailed Guide of Psilotum nudum: Detailed Study Of Psilotum Nudum (Whisk Fern), Classification, Anatomy, Reproduction

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