Cannabaceae

FOXP4
Identifiers
AliasesFOXP4, hFKHLA, forkhead box P4
External IDsOMIM: 608924; MGI: 1921373; HomoloGene: 12536; GeneCards: FOXP4; OMA:FOXP4 - orthologs
Orthologs
SpeciesHumanMouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_001110824
NM_001110825
NM_028767

RefSeq (protein)

NP_001012426
NP_001012427
NP_612466

NP_001104294
NP_001104295
NP_083043
NP_001390898
NP_001390899

Location (UCSC)Chr 6: 41.55 – 41.6 MbChr 17: 48.18 – 48.24 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

Forkhead box protein P4 is a protein that in humans is encoded by the FOXP4 gene.[5]

This gene belongs to subfamily P of the forkhead box (FOX) transcription factor family. Forkhead box transcription factors play important roles in the regulation of tissue- and cell type-specific gene transcription during both development and adulthood. Many members of the forkhead box gene family, including members of subfamily P, have roles in mammalian oncogenesis. This gene may play a role in the development of tumors of the kidney and larynx. Alternative splicing of this gene produces multiple transcript variants, some encoding different isoforms.[5] It also is a major factor in developing Long COVID as such, increasing the chances of developing the little-understood syndrome 1.6 fold, a finding which has major implications for COVID-19 pandemic research.[6]

References[edit]

  1. ^ a b c GRCh38: Ensembl release 89: ENSG00000137166Ensembl, May 2017
  2. ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000023991Ensembl, May 2017
  3. ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. ^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. ^ a b "Entrez Gene: FOXP4 forkhead box P4".
  6. ^ Ledford H (July 11, 2023). "Gene linked to long COVID found in analysis of thousands of patients". Nature. 619 (7970): 445. Bibcode:2023Natur.619..445L. doi:10.1038/d41586-023-02269-2. PMID 37433943. S2CID 259831412 – via www.nature.com.

Further reading[edit]


One thought on “Cannabaceae

  1. Well, that’s interesting to know that Psilotum nudum are known as whisk ferns. Psilotum nudum is the commoner species of the two. While the P. flaccidum is a rare species and is found in the tropical islands. Both the species are usually epiphytic in habit and grow upon tree ferns. These species may also be terrestrial and grow in humus or in the crevices of the rocks.
    View the detailed Guide of Psilotum nudum: Detailed Study Of Psilotum Nudum (Whisk Fern), Classification, Anatomy, Reproduction

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