Cannabaceae

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Etymemazine
Clinical data
Other namesEthylisobutrazine
AHFS/Drugs.comInternational Drug Names
ATC code
  • none
Identifiers
  • 3-(2-ethylphenothiazin-10-yl)-N,N,2-trimethylpropan-1-amine
CAS Number
PubChem CID
ChemSpider
UNII
ChEMBL
CompTox Dashboard (EPA)
Chemical and physical data
FormulaC20H26N2S
Molar mass326.50 g·mol−1
3D model (JSmol)
  • CCC(C=C3)=CC2=C3SC1=CC=CC=C1N2CC(C)CN(C)C
  • InChI=1S/C20H26N2S/c1-5-16-10-11-20-18(12-16)22(14-15(2)13-21(3)4)17-8-6-7-9-19(17)23-20/h6-12,15H,5,13-14H2,1-4H3
  • Key:USKHCLAXJXCWMO-UHFFFAOYSA-N
  (verify)

Etymemazine is an antipsychotic, antihistamine and anticholinergic drug of the phenothiazine chemical class, structurally related to cyamemazine and methotrimeprazine.[1]

Synthesis[edit]

Etymemazine can be synthesized by SN2 alkylation of 2-ethylphenothiazine (1) with 1-dimethylamino-2-methyl-3-chloropropane (2) using sodamide as a base.[2][3]

Synthesis of etymemazine

References[edit]

  1. ^ Milne GW (2002). "Etymemazine". Drugs: Synonyms and Properties (2nd ed.). Aldershot, Hampshire, England: Ashgate. p. 3945. ISBN 978-0-566-08491-1.
  2. ^ GB 789703  (1958 to Rhone Poulenc Sa).
  3. ^ Robert Michel Jacob, et al. U.S. patent 2,837,518 (1956 to Rhone Poulenc Sa)


source: https://en.wikipedia.org/wiki/Etymemazine

One thought on “Cannabaceae”

  1. Well, that’s interesting to know that Psilotum nudum are known as whisk ferns. Psilotum nudum is the commoner species of the two. While the P. flaccidum is a rare species and is found in the tropical islands. Both the species are usually epiphytic in habit and grow upon tree ferns. These species may also be terrestrial and grow in humus or in the crevices of the rocks.
    View the detailed Guide of Psilotum nudum: Detailed Study Of Psilotum Nudum (Whisk Fern), Classification, Anatomy, Reproduction

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