Cannabaceae

Estradiol furoate
Clinical data
Trade namesDi-Folliculine
Other namesEF; 17-Furoylestradiol; 17-(2-Furancarbonyl)estradiol
Routes of
administration
Intramuscular injection
Drug classEstrogen; Estrogen ester
Identifiers
  • [(8R,9S,13S,14S,17S)-3-hydroxy-13-methyl-6,7,8,9,11,12,14,15,16,17-decahydrocyclopenta[a]phenanthren-17-yl] furan-2-carboxylate
CAS Number
PubChem CID
ChemSpider
UNII
CompTox Dashboard (EPA)
Chemical and physical data
FormulaC23H26O4
Molar mass366.457 g·mol−1
3D model (JSmol)
  • C[C@]12CC[C@H]3[C@@H](CCc4cc(O)ccc34)[C@@H]1CC[C@@H]2OC(=O)c5occc5
  • InChI=1S/C23H26O4/c1-23-11-10-17-16-7-5-15(24)13-14(16)4-6-18(17)19(23)8-9-21(23)27-22(25)20-3-2-12-26-20/h2-3,5,7,12-13,17-19,21,24H,4,6,8-11H2,1H3/t17-,18-,19+,21+,23+/m1/s1
  • Key:UZMCMLLMBRERNY-BEARUUAKSA-N

Estradiol furoate (EF), or estradiol 17β-furoate, sold under the brand name Di-Folliculine, is an estrogen medication and estrogen ester which is no longer marketed.[1] It is the C17β furoate ester of estradiol.[1] Estradiol benzoate has also been marketed under the brand name Di-Folliculine, and should not be confused with estradiol furoate.[2]

The duration of action of the related estradiol ester estradiol 3-furoate by intramuscular injection was studied in women in 1952.[3] Its duration in oil solution was found to be similar to that of estradiol benzoate in oil solution and shorter than that of estradiol dipropionate in oil solution.[3]

See also

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References

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  1. ^ a b Elks J (14 November 2014). The Dictionary of Drugs: Chemical Data: Chemical Data, Structures and Bibliographies. Springer. p. 898. ISBN 978-1-4757-2085-3.
  2. ^ Pharmaceutical Abstracts. American Pharmaceutical Association. 1941. p. 149.
  3. ^ a b Ferin J (January 1952). "Relative duration of action of natural and synthetic estrogens administered parenterally in women with estrogen deficiency". The Journal of Clinical Endocrinology and Metabolism. 12 (1): 28–35. doi:10.1210/jcem-12-1-28. PMID 14907837.


One thought on “Cannabaceae

  1. Well, that’s interesting to know that Psilotum nudum are known as whisk ferns. Psilotum nudum is the commoner species of the two. While the P. flaccidum is a rare species and is found in the tropical islands. Both the species are usually epiphytic in habit and grow upon tree ferns. These species may also be terrestrial and grow in humus or in the crevices of the rocks.
    View the detailed Guide of Psilotum nudum: Detailed Study Of Psilotum Nudum (Whisk Fern), Classification, Anatomy, Reproduction

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