Cannabaceae

thcscience_admin
Dinoxyline
Clinical data
ATC code
  • none
Identifiers
  • 8,9-dihydroxy-1,2,3,11b-tetrahydrochromeno[4,3,2,-de]isoquinoline
CAS Number
PubChem CID
ChemSpider
UNII
CompTox Dashboard (EPA)
Chemical and physical data
FormulaC15H13NO3
Molar mass255.273 g·mol−1
3D model (JSmol)
  • c3ccc(Oc24)c1c3CNCC1c4ccc(O)c2O
  • InChI=1S/C15H13NO3/c17-11-5-4-9-10-7-16-6-8-2-1-3-12(13(8)10)19-15(9)14(11)18/h1-5,10,16-18H,6-7H2
  • Key:QOHSTVKJXZTEOL-UHFFFAOYSA-N
  (verify)

Dinoxyline is a synthetic compound developed for scientific research, which acts as a potent full agonist at all five dopamine receptor subtypes.[1][2][3]

References

[edit]
  1. ^ Grubbs RA, Lewis MM, Owens-Vance C, Gay EA, Jassen AK, Mailman RB, Nichols DE (March 2004). "8,9-dihydroxy-1,2,3,11b-tetrahydrochromeno[4,3,2,-de]isoquinoline (dinoxyline), a high affinity and potent agonist at all dopamine receptor isoforms". Bioorganic & Medicinal Chemistry. 12 (6): 1403–12. doi:10.1016/j.bmc.2004.01.008. PMID 15018913.
  2. ^ Ryman-Rasmussen JP, Nichols DE, Mailman RB (October 2005). "Differential activation of adenylate cyclase and receptor internalization by novel dopamine D1 receptor agonists". Molecular Pharmacology. 68 (4): 1039–48. doi:10.1124/mol.105.012153. PMID 15985612. S2CID 14398107.
  3. ^ Zhang J, Xiong B, Zhen X, Zhang A (March 2009). "Dopamine D1 receptor ligands: where are we now and where are we going". Medicinal Research Reviews. 29 (2): 272–94. doi:10.1002/med.20130. PMID 18642350. S2CID 25334596.


source: https://en.wikipedia.org/wiki/Dinoxyline

One thought on “Cannabaceae”

  1. Well, that’s interesting to know that Psilotum nudum are known as whisk ferns. Psilotum nudum is the commoner species of the two. While the P. flaccidum is a rare species and is found in the tropical islands. Both the species are usually epiphytic in habit and grow upon tree ferns. These species may also be terrestrial and grow in humus or in the crevices of the rocks.
    View the detailed Guide of Psilotum nudum: Detailed Study Of Psilotum Nudum (Whisk Fern), Classification, Anatomy, Reproduction

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