Cannabaceae

Dacetuzumab
Monoclonal antibody
TypeWhole antibody
SourceHumanized (from mouse)
TargetCD40
Clinical data
Other namesSGN-40
ATC code
  • none
Identifiers
CAS Number
ChemSpider
  • none
UNII
Chemical and physical data
FormulaC6452H9964N1732O1998S42
Molar mass145111.33 g·mol−1
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Dacetuzumab (also known as SGN-40 or huS2C6) is a humanized monoclonal antibody[1] being developed for the treatment of CD40-positive cancers like non-Hodgkin's lymphoma[2] and hematological malignancies.[3]

This drug was developed by Seattle Genetics, Inc.

References

[edit]
  1. ^ Statement On A Nonproprietary Name Adopted By The USAN Council - Dacetuzumab, American Medical Association.
  2. ^ Advani R, Forero-Torres A, Furman RR, Rosenblatt JD, Younes A, Ren H, et al. (September 2009). "Phase I study of the humanized anti-CD40 monoclonal antibody dacetuzumab in refractory or recurrent non-Hodgkin's lymphoma". Journal of Clinical Oncology. 27 (26): 4371–7. doi:10.1200/JCO.2008.21.3017. PMID 19636010.
  3. ^ Khubchandani S, Czuczman MS, Hernandez-Ilizaliturri FJ (June 2009). "Dacetuzumab, a humanized mAb against CD40 for the treatment of hematological malignancies". Current Opinion in Investigational Drugs. 10 (6): 579–87. PMID 19513947.

One thought on “Cannabaceae

  1. Well, that’s interesting to know that Psilotum nudum are known as whisk ferns. Psilotum nudum is the commoner species of the two. While the P. flaccidum is a rare species and is found in the tropical islands. Both the species are usually epiphytic in habit and grow upon tree ferns. These species may also be terrestrial and grow in humus or in the crevices of the rocks.
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