Cannabaceae

DLX2
Identifiers
AliasesDLX2, TES-1, TES1, AW121999, Dlx-2, distal-less homeobox 2
External IDsOMIM: 126255; MGI: 94902; HomoloGene: 3244; GeneCards: DLX2; OMA:DLX2 - orthologs
Orthologs
SpeciesHumanMouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_004405

NM_010054

RefSeq (protein)

NP_004396
NP_004396.1

NP_034184

Location (UCSC)Chr 2: 172.1 – 172.1 MbChr 2: 71.37 – 71.38 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

Homeobox protein DLX-2 is a protein that in humans is encoded by the DLX2 gene.[5][6]

Many vertebrate homeo box-containing genes have been identified on the basis of their sequence similarity with Drosophila developmental genes. Members of the Dlx gene family contain a homeobox that is related to that of Distal-less (Dll), a gene expressed in the head and limbs of the developing fruit fly. The Distal-less (Dlx) family of genes comprises at least 6 different members, DLX1-DLX6. The DLX proteins are postulated to play a role in forebrain and craniofacial development. This gene is located in a tail-to-tail configuration with another member of the gene family on the long arm of chromosome 2.[6]

Interactions[edit]

DLX2 has been shown to interact with DLX5,[7] MSX1[7] and Msh homeobox 2.[7]

References[edit]

  1. ^ a b c GRCh38: Ensembl release 89: ENSG00000115844Ensembl, May 2017
  2. ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000023391Ensembl, May 2017
  3. ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. ^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. ^ Ozcelik T, Porteus MH, Rubenstein JL, Francke U (Sep 1992). "DLX2 (TES1), a homeobox gene of the Distal-less family, assigned to conserved regions on human and mouse chromosomes 2". Genomics. 13 (4): 1157–61. doi:10.1016/0888-7543(92)90031-M. PMID 1354641.
  6. ^ a b "Entrez Gene: DLX2 distal-less homeobox 2".
  7. ^ a b c Zhang, H; Hu G; Wang H; Sciavolino P; Iler N; Shen M M; Abate-Shen C (May 1997). "Heterodimerization of Msx and Dlx homeoproteins results in functional antagonism". Mol. Cell. Biol. 17 (5). UNITED STATES: 2920–32. doi:10.1128/mcb.17.5.2920. ISSN 0270-7306. PMC 232144. PMID 9111364.

Further reading[edit]

One thought on “Cannabaceae

  1. Well, that’s interesting to know that Psilotum nudum are known as whisk ferns. Psilotum nudum is the commoner species of the two. While the P. flaccidum is a rare species and is found in the tropical islands. Both the species are usually epiphytic in habit and grow upon tree ferns. These species may also be terrestrial and grow in humus or in the crevices of the rocks.
    View the detailed Guide of Psilotum nudum: Detailed Study Of Psilotum Nudum (Whisk Fern), Classification, Anatomy, Reproduction

Leave a Reply