Cannabaceae

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DCPG
Identifiers
  • 4-[(1S)-1-amino-2-hydroxy-2-oxoethyl]phthalic acid
CAS Number
PubChem CID
IUPHAR/BPS
ChemSpider
UNII
CompTox Dashboard (EPA)
ECHA InfoCard100.161.870 Edit this at Wikidata
Chemical and physical data
FormulaC10H9NO6
Molar mass239.183 g·mol−1
3D model (JSmol)
  • O=C(O)[C@@H](N)c1cc(c(C(=O)O)cc1)C(=O)O
  • InChI=1S/C10H9NO6/c11-7(10(16)17)4-1-2-5(8(12)13)6(3-4)9(14)15/h1-3,7H,11H2,(H,12,13)(H,14,15)(H,16,17)/t7-/m0/s1 ☒N
  • Key:IJVMOGKBEVRBPP-ZETCQYMHSA-N ☒N
 ☒NcheckY (what is this?)  (verify)

DCPG ((S)-3,4-DCPG) is a drug used in scientific research, which acts as a potent and subtype-selective agonist for the metabotropic glutamate receptor mGluR8. It has anticonvulsant effects in animal studies,[1][2] and has also been investigated as a possible treatment for hyperalgesia.[3]

References[edit]

  1. ^ Moldrich RX, Chapman AG, De Sarro G, Meldrum BS (August 2003). "Glutamate metabotropic receptors as targets for drug therapy in epilepsy". European Journal of Pharmacology. 476 (1–2): 3–16. doi:10.1016/s0014-2999(03)02149-6. PMID 12969743.
  2. ^ Folbergrová J, Druga R, Haugvicová R, Mares P, Otáhal J (March 2008). "Anticonvulsant and neuroprotective effect of (S)-3,4-dicarboxyphenylglycine against seizures induced in immature rats by homocysteic acid". Neuropharmacology. 54 (4): 665–75. doi:10.1016/j.neuropharm.2007.11.015. PMID 18191956. S2CID 20697899.
  3. ^ Marabese I, de Novellis V, Palazzo E, Scafuro MA, Vita D, Rossi F, Maione S (February 2007). "Effects of (S)-3,4-DCPG, an mGlu8 receptor agonist, on inflammatory and neuropathic pain in mice". Neuropharmacology. 52 (2): 253–62. doi:10.1016/j.neuropharm.2006.04.006. PMID 17113112. S2CID 25646746.
source: https://en.wikipedia.org/wiki/DCPG

One thought on “Cannabaceae”

  1. Well, that’s interesting to know that Psilotum nudum are known as whisk ferns. Psilotum nudum is the commoner species of the two. While the P. flaccidum is a rare species and is found in the tropical islands. Both the species are usually epiphytic in habit and grow upon tree ferns. These species may also be terrestrial and grow in humus or in the crevices of the rocks.
    View the detailed Guide of Psilotum nudum: Detailed Study Of Psilotum Nudum (Whisk Fern), Classification, Anatomy, Reproduction

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