Clinical data | |
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Other names | RU-56279 |
Drug class | Nonsteroidal antiandrogen |
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Formula | C13H10F3N3O2 |
Molar mass | 297.237 g·mol−1 |
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Cyanonilutamide (developmental code name RU-56279) is a nonsteroidal antiandrogen which was never marketed.[1][2] Both RU-56187 and RU-58841 appear to be prodrugs of cyanonilutamide in vivo in animals.[2] It has relatively low affinity for the androgen receptor but nonetheless shows significant antiandrogenic activity in animals.[2]
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References[edit]
- ^ Gryder BE, Akbashev MJ, Rood MK, Raftery ED, Meyers WM, Dillard P, Khan S, Oyelere AK (November 2013). "Selectively targeting prostate cancer with antiandrogen equipped histone deacetylase inhibitors". ACS Chem. Biol. 8 (11): 2550–60. doi:10.1021/cb400542w. PMC 3836611. PMID 24004176.
- ^ a b c Cousty-Berlin D, Bergaud B, Bruyant MC, Battmann T, Branche C, Philibert D (October 1994). "Preliminary pharmacokinetics and metabolism of novel non-steroidal antiandrogens in the rat: relation of their systemic activity to the formation of a common metabolite". J. Steroid Biochem. Mol. Biol. 51 (1–2): 47–55. doi:10.1016/0960-0760(94)90114-7. PMID 7947350. S2CID 29752252.
Well, that’s interesting to know that Psilotum nudum are known as whisk ferns. Psilotum nudum is the commoner species of the two. While the P. flaccidum is a rare species and is found in the tropical islands. Both the species are usually epiphytic in habit and grow upon tree ferns. These species may also be terrestrial and grow in humus or in the crevices of the rocks.
View the detailed Guide of Psilotum nudum: Detailed Study Of Psilotum Nudum (Whisk Fern), Classification, Anatomy, Reproduction