Cannabaceae

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Buclizine
Clinical data
AHFS/Drugs.comMicromedex Detailed Consumer Information
ATC code
Identifiers
  • (RS)-1-[(4-chlorophenyl)- phenyl-methyl]-4- [(4-tert-butylphenyl) methyl] piperazine
CAS Number
PubChem CID
IUPHAR/BPS
DrugBank
ChemSpider
UNII
ChEBI
ChEMBL
CompTox Dashboard (EPA)
ECHA InfoCard100.001.317 Edit this at Wikidata
Chemical and physical data
FormulaC28H33ClN2
Molar mass433.04 g·mol−1
3D model (JSmol)
ChiralityRacemic mixture
  • Clc1ccc(cc1)C(c2ccccc2)N3CCN(CC3)Cc4ccc(cc4)C(C)(C)C
  • InChI=1S/C28H33ClN2/c1-28(2,3)25-13-9-22(10-14-25)21-30-17-19-31(20-18-30)27(23-7-5-4-6-8-23)24-11-15-26(29)16-12-24/h4-16,27H,17-21H2,1-3H3 checkY
  • Key:MOYGZHXDRJNJEP-UHFFFAOYSA-N checkY
 ☒NcheckY (what is this?)  (verify)

Buclizine is an antihistamine and anticholinergic of the diphenylmethylpiperazine group. It is considered to be an antiemetic, similar to meclizine.[1]

In the United Kingdom, buclizine is one of three drugs contained in Migraleve tablets, marketed by McNeil Healthcare for migraines.[2]

References[edit]

  1. ^ Mostafa GA, Al-Badr AA (2011). "Buclizine". Profiles Drug Subst Excip Relat Methodol. Profiles of Drug Substances, Excipients and Related Methodology. 36: 1–33. doi:10.1016/B978-0-12-387667-6.00001-4. ISBN 9780123876676. PMID 22469258.
  2. ^ Behrendt WA, Cserepes J (1985). "Acute toxicity and analgesic action of a combination of buclizine, codeine and paracetamol ('Migraleve') in tablet and suppository form in rats". Pharmatherapeutica. 4 (5): 322–31. PMID 4070325.
source: https://en.wikipedia.org/wiki/Buclizine

One thought on “Cannabaceae”

  1. Well, that’s interesting to know that Psilotum nudum are known as whisk ferns. Psilotum nudum is the commoner species of the two. While the P. flaccidum is a rare species and is found in the tropical islands. Both the species are usually epiphytic in habit and grow upon tree ferns. These species may also be terrestrial and grow in humus or in the crevices of the rocks.
    View the detailed Guide of Psilotum nudum: Detailed Study Of Psilotum Nudum (Whisk Fern), Classification, Anatomy, Reproduction

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