Cannabaceae

Benoxathian
Names
IUPAC name
N-(2,3-Dihydro-1,4-benzoxathiin-2-ylmethyl)-2-(2,6-dimethoxyphenoxy)ethanamine
Identifiers
3D model (JSmol)
ChemSpider
  • InChI=1S/C19H23NO4S/c1-21-16-7-5-8-17(22-2)19(16)23-11-10-20-12-14-13-25-18-9-4-3-6-15(18)24-14/h3-9,14,20H,10-13H2,1-2H3
    Key: QAUVAHYHKLRJCQ-UHFFFAOYSA-N
  • InChI=1/C19H23NO4S/c1-21-16-7-5-8-17(22-2)19(16)23-11-10-20-12-14-13-25-18-9-4-3-6-15(18)24-14/h3-9,14,20H,10-13H2,1-2H3
    Key: QAUVAHYHKLRJCQ-UHFFFAOYAX
  • COC1=C(C(=CC=C1)OC)OCCNCC2CSC3=CC=CC=C3O2
Properties
C19H23NO4S
Molar mass 361.46 g·mol−1
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).

Benoxathian is an α1-adrenergic receptor antagonist.[1] It was studied in animals for its antihypertensive (blood pressure lowering) effects in the 1980s.[2]

References[edit]

  1. ^ Nagayasu, K; Kitaichi, M; Nishitani, N; Asaoka, N; Shirakawa, H; Nakagawa, T; Kaneko, S (2013). "Chronic effects of antidepressants on serotonin release in rat raphe slice cultures: High potency of milnacipran in the augmentation of serotonin release". The International Journal of Neuropsychopharmacology. 16 (10): 2295–306. doi:10.1017/S1461145713000771. PMID 23920436.
  2. ^ Massi, M.; Venturi, F.; Brasili, L.; Melchiorre, C. (1986). "Hypotensive effect in dogs and rats of intravenous injections of the alpha 1-adrenoreceptor antagonist benoxathian". Pharmacological Research Communications. 18 (9): 813–829. doi:10.1016/0031-6989(86)90132-3. PMID 2879293.



One thought on “Cannabaceae

  1. Well, that’s interesting to know that Psilotum nudum are known as whisk ferns. Psilotum nudum is the commoner species of the two. While the P. flaccidum is a rare species and is found in the tropical islands. Both the species are usually epiphytic in habit and grow upon tree ferns. These species may also be terrestrial and grow in humus or in the crevices of the rocks.
    View the detailed Guide of Psilotum nudum: Detailed Study Of Psilotum Nudum (Whisk Fern), Classification, Anatomy, Reproduction

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