THC Science

AUTS2
Identifiers
Aliases	AUTS2, FBRSL2, MRD26, activator of transcription and developmental regulator, activator of transcription and developmental regulator AUTS2
External IDs	OMIM: 607270; MGI: 1919847; HomoloGene: 22907; GeneCards: AUTS2; OMA:AUTS2 - orthologs
Gene location (Human)
Chr.	Chromosome 7 (human)
End	70,793,506 bp
Gene location (Mouse)
Chr.	Chromosome 5 (mouse)
End	132,572,183 bp
RNA expression pattern
	Top expressed in
	Top expressed in
	More reference expression data
	n/a
Gene ontology
Molecular function
Cellular component
Biological process
	Sources:Amigo / QuickGO
Orthologs
	26053
	319974
	ENSG00000158321
	ENSMUSG00000029673
	Q8WXX7
	A0A087WPF7
	NM_001127231; NM_001127232; NM_015570
	NM_001363480
	NP_001120703; NP_001120704; NP_056385
	NP_001350409
	Wikidata
View/Edit Human	View/Edit Mouse

AUTS2, activator of transcription and developmental regulator is a protein that in humans is encoded by the AUTS2 gene. ^[5]

Function

This gene has been implicated in neurodevelopment and as a candidate gene for numerous neurological disorders, including autism spectrum disorders, intellectual disability, and developmental delay. Mutations in this gene have also been associated with non-neurological disorders, such as acute lymphoblastic leukemia, aging of the skin, early-onset androgenetic alopecia, and certain cancers.

References

^ ^a ^b ^c GRCh38: Ensembl release 89: ENSG00000158321 – Ensembl, May 2017
^ ^a ^b ^c GRCm38: Ensembl release 89: ENSMUSG00000029673 – Ensembl, May 2017
^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Entrez Gene: AUTS2, activator of transcription and developmental regulator". Retrieved 2017-09-12.

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This article incorporates text from the United States National Library of Medicine, which is in the public domain.

[refGRCh38Ensembl-1] GRCh38: Ensembl release 89: ENSG00000158321 – Ensembl, May 2017

[refGRCm38Ensembl-2] GRCm38: Ensembl release 89: ENSMUSG00000029673 – Ensembl, May 2017

[3] "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[4] "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[entrez-5] "Entrez Gene: AUTS2, activator of transcription and developmental regulator". Retrieved 2017-09-12.

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