Cannabaceae

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8-OH-PBZI
Clinical data
ATC code
  • none
Identifiers
  • (3aS,9bR)-3-propyl-1,2,3a,4,5,9b-hexahydrobenzo[e]indol-8-ol
CAS Number
PubChem CID
ChemSpider
CompTox Dashboard (EPA)
Chemical and physical data
FormulaC15H21NO
Molar mass231.339 g·mol−1
3D model (JSmol)
  • CCCN1CC[C@H]2[C@@H]1CCC3=C2C=C(C=C3)O
  • InChI=1S/C15H21NO/c1-2-8-16-9-7-13-14-10-12(17)5-3-11(14)4-6-15(13)16/h3,5,10,13,15,17H,2,4,6-9H2,1H3/t13-,15+/m1/s1 checkY
  • Key:LJDRQPOQHHOXHM-HIFRSBDPSA-N checkY
  (verify)

8-OH-PBZI is a drug used in scientific research which acts as a potent and selective agonist for the dopamine D3 receptor.[1][2][3]

References[edit]

  1. ^ Scheideler MA, Martin J, Hohlweg R, Rasmussen JS, Naerum L, Ludvigsen TS, et al. (November 1997). "The preferential dopamine D3 receptor agonist cis-8-OH-PBZI induces limbic Fos expression in rat brain". European Journal of Pharmacology. 339 (2–3): 261–70. doi:10.1016/S0014-2999(97)01372-1. PMID 9473144.
  2. ^ Fink-Jensen A, Nielsen EB, Hansen L, Scheideler MA (January 1998). "Behavioral and neurochemical effects of the preferential dopamine D3 receptor agonist cis-8-OH-PBZI". European Journal of Pharmacology. 342 (2–3): 153–61. doi:10.1016/S0014-2999(97)01494-5. PMID 9548380.
  3. ^ Malik P, Andersen MB, Peacock L (August 2004). "The effects of dopamine D3 agonists and antagonists in a nonhuman primate model of tardive dyskinesia". Pharmacology, Biochemistry, and Behavior. 78 (4): 805–10. doi:10.1016/j.pbb.2004.05.019. PMID 15301939. S2CID 19410897.
source: https://en.wikipedia.org/wiki/8-OH-PBZI

One thought on “Cannabaceae”

  1. Well, that’s interesting to know that Psilotum nudum are known as whisk ferns. Psilotum nudum is the commoner species of the two. While the P. flaccidum is a rare species and is found in the tropical islands. Both the species are usually epiphytic in habit and grow upon tree ferns. These species may also be terrestrial and grow in humus or in the crevices of the rocks.
    View the detailed Guide of Psilotum nudum: Detailed Study Of Psilotum Nudum (Whisk Fern), Classification, Anatomy, Reproduction

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