Cannabaceae

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1-Benzyl-4-[2-(diphenylmethoxy)­ethyl]piperidine
Names
Preferred IUPAC name
1-Benzyl-4-[2-(diphenylmethoxy)­ethyl]piperidine
Identifiers
3D model (JSmol)
ChEMBL
ChemSpider
  • InChI=1S/C27H31NO/c1-4-10-24(11-5-1)22-28-19-16-23(17-20-28)18-21-29-27(25-12-6-2-7-13-25)26-14-8-3-9-15-26/h1-15,23,27H,16-22H2 checkY
    Key: WRSJONWBAYSODC-UHFFFAOYSA-N checkY
  • InChI=1/C27H31NO/c1-4-10-24(11-5-1)22-28-19-16-23(17-20-28)18-21-29-27(25-12-6-2-7-13-25)26-14-8-3-9-15-26/h1-15,23,27H,16-22H2
    Key: WRSJONWBAYSODC-UHFFFAOYAC
  • O(C(c1ccccc1)c2ccccc2)CCC4CCN(Cc3ccccc3)CC4
Properties
C27H31NO
Molar mass 385.551 g·mol−1
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
☒N verify (what is checkY☒N ?)

1-Benzyl-4-[2-(diphenyl​methoxy)​ethyl]​piperidine is a stimulant of the piperidine class which acts as a potent and selective dopamine reuptake inhibitor.[1][2] It is closely related to vanoxerine and GBR-12,935, which in contrast are piperazines.

See also[edit]

References[edit]

  1. ^ Dutta AK, Coffey LL, Reith ME (January 1997). "Highly selective, novel analogs of 4-[2-(diphenylmethoxy)ethyl]-1-benzylpiperidine for the dopamine transporter: effect of different aromatic substitutions on their affinity and selectivity". Journal of Medicinal Chemistry. 40 (1): 35–43. doi:10.1021/jm960638e. PMID 9016326.
  2. ^ Dutta AK, Davis MC, Fei XS, Beardsley PM, Cook CD, Reith ME (January 2002). "Expansion of structure-activity studies of piperidine analogues of 1-[2-(diphenylmethoxy)ethyl]-4-(3-phenylpropyl)piperazine (GBR 12935) compounds by altering substitutions in the N-benzyl moiety and behavioral pharmacology of selected molecules". Journal of Medicinal Chemistry. 45 (3): 654–62. doi:10.1021/jm010316x. PMID 11806716.
source: https://en.wikipedia.org/wiki/1-Benzyl-4-(2-(diphenylmethoxy)ethyl)piperidine

One thought on “Cannabaceae”

  1. Well, that’s interesting to know that Psilotum nudum are known as whisk ferns. Psilotum nudum is the commoner species of the two. While the P. flaccidum is a rare species and is found in the tropical islands. Both the species are usually epiphytic in habit and grow upon tree ferns. These species may also be terrestrial and grow in humus or in the crevices of the rocks.
    View the detailed Guide of Psilotum nudum: Detailed Study Of Psilotum Nudum (Whisk Fern), Classification, Anatomy, Reproduction

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