Cannabaceae

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α-Zearalenol
Clinical data
Other namesalpha-Zearalenol; trans-Zearalenol; 2,4-Dihydroxy-6-(6α,10-dihydroxy-trans-1-undecenyl)benzoic acid μ-lactone
Identifiers
  • (2E,7R,11S)-7,15,17-trihydroxy-11-methyl-12-oxabicyclo[12.4.0]octadeca-1(14),2,15,17-tetraen-13-one
CAS Number
PubChem CID
ChemSpider
UNII
KEGG
ChEBI
ChEMBL
CompTox Dashboard (EPA)
ECHA InfoCard100.264.264 Edit this at Wikidata
Chemical and physical data
FormulaC18H24O5
Molar mass320.385 g·mol−1
3D model (JSmol)
  • C[C@H]1CCC[C@@H](CCC/C=C/C2=CC(=CC(=C2C(=O)O1)O)O)O
  • InChI=1S/C18H24O5/c1-12-6-5-9-14(19)8-4-2-3-7-13-10-15(20)11-16(21)17(13)18(22)23-12/h3,7,10-12,14,19-21H,2,4-6,8-9H2,1H3/b7-3+/t12-,14+/m0/s1
  • Key:FPQFYIAXQDXNOR-QDKLYSGJSA-N

α-Zearalenol is a nonsteroidal estrogen of the resorcylic acid lactone group related to mycoestrogens found in Fusarium spp.[1] It is the α-epimer of β-zearalenol.[2] Along with β-zearalenol, it is a major metabolite of zearalenone formed mainly in the liver but also to a lesser extent in the intestines during first-pass metabolism.[2][3] A relatively low proportion of β-zearalenol is metabolized from zearalenone compared to α-zearalenol in humans.[3] α-Zearalenol is about three to four times more potent as an estrogen relative to zearalenone.[1]

See also[edit]

References[edit]

  1. ^ a b Chelkowski J (28 June 2014). Fusarium: Mycotoxins, Taxonomy, Pathogenicity. Elsevier Science. pp. 85–. ISBN 978-1-4832-9785-9.
  2. ^ a b Magan N, Olsen M (2004). Mycotoxins in Food: Detection and Control. Woodhead Publishing. pp. 356–. ISBN 978-1-85573-733-4.
  3. ^ a b Eriksen GS (1998). Fusarium Toxins in Cereals: A Risk Assessment. Nordic Council of Ministers. pp. 61–. ISBN 978-92-893-0149-7.
source: https://en.wikipedia.org/wiki/%CE%91-Zearalenol

One thought on “Cannabaceae”

  1. Well, that’s interesting to know that Psilotum nudum are known as whisk ferns. Psilotum nudum is the commoner species of the two. While the P. flaccidum is a rare species and is found in the tropical islands. Both the species are usually epiphytic in habit and grow upon tree ferns. These species may also be terrestrial and grow in humus or in the crevices of the rocks.
    View the detailed Guide of Psilotum nudum: Detailed Study Of Psilotum Nudum (Whisk Fern), Classification, Anatomy, Reproduction

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