Protein-coding gene in the species Homo sapiens
Syntaxin-12 is a protein that in humans is encoded by the STX12 gene .[5] [6]
Interactions [ edit ] STX12 has been shown to interact with PLDN .[7]
References [ edit ]
^ a b c GRCh38: Ensembl release 89: ENSG00000117758 – Ensembl , May 2017^ a b c GRCm38: Ensembl release 89: ENSMUSG00000028879 – Ensembl , May 2017^ "Human PubMed Reference:" . National Center for Biotechnology Information, U.S. National Library of Medicine .^ "Mouse PubMed Reference:" . National Center for Biotechnology Information, U.S. National Library of Medicine .^ Tang BL, Tan AE, Lim LK, Lee SS, Low DY, Hong W (March 1998). "Syntaxin 12, a member of the syntaxin family localized to the endosome" . The Journal of Biological Chemistry . 273 (12): 6944–50. doi :10.1074/jbc.273.12.6944 PMID 9507000 . ^ "Entrez Gene: STX12 syntaxin 12" .^ Huang L, Kuo YM, Gitschier J (November 1999). "The pallid gene encodes a novel, syntaxin 13-interacting protein involved in platelet storage pool deficiency". Nature Genetics . 23 (3): 329–32. doi :10.1038/15507 . PMID 10610180 . S2CID 22843205 .
Further reading [ edit ]
Falcón-Pérez JM, Dell'Angelica EC (April 2002). "The pallidin (Pldn) gene and the role of SNARE proteins in melanosome biogenesis" . Pigment Cell Research . 15 (2): 82–6. doi :10.1034/j.1600-0749.2002.1r082.x PMID 11936273 . Andersson B, Wentland MA, Ricafrente JY, Liu W, Gibbs RA (April 1996). "A "double adaptor" method for improved shotgun library construction". Analytical Biochemistry . 236 (1): 107–13. doi :10.1006/abio.1996.0138 . PMID 8619474 . Yu W, Andersson B, Worley KC, Muzny DM, Ding Y, Liu W, Ricafrente JY, Wentland MA, Lennon G, Gibbs RA (April 1997). "Large-scale concatenation cDNA sequencing" . Genome Research . 7 (4): 353–8. doi :10.1101/gr.7.4.353 . PMC 139146 PMID 9110174 . Advani RJ, Bae HR, Bock JB, Chao DS, Doung YC, Prekeris R, Yoo JS, Scheller RH (April 1998). "Seven novel mammalian SNARE proteins localize to distinct membrane compartments" . The Journal of Biological Chemistry . 273 (17): 10317–24. doi :10.1074/jbc.273.17.10317 PMID 9553086 . Prekeris R, Klumperman J, Chen YA, Scheller RH (November 1998). "Syntaxin 13 mediates cycling of plasma membrane proteins via tubulovesicular recycling endosomes" . The Journal of Cell Biology . 143 (4): 957–71. doi :10.1083/jcb.143.4.957 . PMC 2132958 PMID 9817754 . Steegmaier M, Yang B, Yoo JS, Huang B, Shen M, Yu S, Luo Y, Scheller RH (December 1998). "Three novel proteins of the syntaxin/SNAP-25 family" . The Journal of Biological Chemistry . 273 (51): 34171–9. doi :10.1074/jbc.273.51.34171 PMID 9852078 . McBride HM, Rybin V, Murphy C, Giner A, Teasdale R, Zerial M (August 1999). "Oligomeric complexes link Rab5 effectors with NSF and drive membrane fusion via interactions between EEA1 and syntaxin 13" . Cell . 98 (3): 377–86. doi :10.1016/S0092-8674(00)81966-2 PMID 10458612 . S2CID 2516425 . Huang L, Kuo YM, Gitschier J (November 1999). "The pallid gene encodes a novel, syntaxin 13-interacting protein involved in platelet storage pool deficiency". Nature Genetics . 23 (3): 329–32. doi :10.1038/15507 . PMID 10610180 . S2CID 22843205 . Minakami R, Kato A, Sugiyama H (June 2000). "Interaction of Vesl-1L/Homer 1c with syntaxin 13". Biochemical and Biophysical Research Communications . 272 (2): 466–71. doi :10.1006/bbrc.2000.2777 . PMID 10833436 . Hirling H, Steiner P, Chaperon C, Marsault R, Regazzi R, Catsicas S (June 2000). "Syntaxin 13 is a developmentally regulated SNARE involved in neurite outgrowth and endosomal trafficking" . The European Journal of Neuroscience . 12 (6): 1913–23. doi :10.1046/j.1460-9568.2000.00076.x PMID 10886332 . S2CID 19547759 . Steiner P, Sarria JC, Glauser L, Magnin S, Catsicas S, Hirling H (June 2002). "Modulation of receptor cycling by neuron-enriched endosomal protein of 21 kD" . The Journal of Cell Biology . 157 (7): 1197–209. doi :10.1083/jcb.200202022 . PMC 2173541 PMID 12070131 . Sun W, Yan Q, Vida TA, Bean AJ (July 2003). "Hrs regulates early endosome fusion by inhibiting formation of an endosomal SNARE complex" . The Journal of Cell Biology . 162 (1): 125–37. doi :10.1083/jcb.200302083 . PMC 2172712 PMID 12847087 . Bared SM, Buechler C, Boettcher A, Dayoub R, Sigruener A, Grandl M, Rudolph C, Dada A, Schmitz G (December 2004). "Association of ABCA1 with syntaxin 13 and flotillin-1 and enhanced phagocytosis in tangier cells" . Molecular Biology of the Cell . 15 (12): 5399–407. doi :10.1091/mbc.E04-03-0182 . PMC 532019 PMID 15469992 . Olsen JV, Blagoev B, Gnad F, Macek B, Kumar C, Mortensen P, Mann M (November 2006). "Global, in vivo, and site-specific phosphorylation dynamics in signaling networks" . Cell . 127 (3): 635–48. doi :10.1016/j.cell.2006.09.026 PMID 17081983 . S2CID 7827573 .
External links [ edit ] PDBe-KB provides an overview of all the structure information available in the PDB for Human Syntaxin-12
PDB gallery
2dnx : Solution structure of RSGI RUH-063, an N-terminal domain of Syntaxin 12 from human cDNA
2nps : Crystal Structure of the Early Endosomal SNARE Complex
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